δ -9-反式四氢大麻酚的合成及生物活性研究进展

Yan-ling Song, Baina Li, Yan-qiu Meng
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引用次数: 0

摘要

大麻的主要精神活性成分- δ -9-反式四氢大麻酚(Δ9-trans-THC)在大约40年前由Gaoni和Mechoulam首次阐明,已被证明具有多种生理功能,包括神经系统生物活性、免疫调节生物活性、抗癌生物活性等。本文综述了Δ9-trans-THC的全合成及其生物活性。
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Advances in Studies on Synthesis and Biological Activity of Delta-9-trans-Tetrahydrocannabinol
The main psychoactive constituent of marijuana, delta-9-trans-tetrahydrocannabinol (Δ9-trans-THC), first elucidated about 40 years ago by Gaoni and Mechoulam, has been shown to possess versatility physiological functions including nervous system bioactivities, immune modulation bioactivities, anticancer bioactivities and so on. This review summarized the total synthesis and biological activities of Δ9-trans-THC.
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