子痫前期及其相关危险因素:加兹温省的病例对照研究

M. Mirabedini, H. Pakniat, M. Mahdavi, S. A. Razavi, Ali Emami, Ali Sarbazi Golezari
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摘要

背景:子痫前期是妊娠期常见疾病之一。其特点是在妊娠后半期出现高血压和蛋白尿。它也是孕妇死亡的三大原因之一。目的:研究伊朗加兹温省科萨医院转诊妇女子痫前期的危险因素。方法:本病例-对照研究回顾2016年在科萨医院转诊的7855例孕妇,其中171例重度先兆子痫住院患者为病例组,171例存在分娩问题的患者为对照组。然后,我们比较了收集到的风险因素数据,如子痫前期病史、高血压、吸烟、糖尿病、不孕、双胞胎和体重指数。结果:子痫前期孕妇的平均±SD年龄为31.19±6.42岁,四分位数间隔为26 ~ 35岁。子痫前期病史(P=0.02)、高血压病史(P=0.001)、体重指数(P=0.001)均显著高于对照组。此外,糖尿病史、不孕症或双胞胎与子痫前期无显著关系(P<0.05)。结论:本研究显示,有子痫前期病史、高血压和体重指数的危险因素在病例组和对照组之间存在显著差异。
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Preeclampsia and Its Associated Risk Factors: A Case-control Study in Qazvin Province
Background: Preeclampsia is one of the common disorders in pregnancy. It is characterized by hypertension and proteinuria in the second half of pregnancy. It is also one of the three main causes of death in pregnant women. Objective: This study investigated the risk factors of preeclampsia in women referred to Kowsar Hospital in Qazvin Province, Iran. Methods: In this case-control study, after reviewing 7855 cases of pregnant women referred to Kowsar Hospital in 2016, 171 hospitalized patients with severe preeclampsia were put in the case group, and 171 patients with delivery problems were in the control group. Then, we compared the collected data about risk factors, such as a history of preeclampsia, hypertension, smoking, diabetes mellitus, infertility, twin, and body mass index, in both groups. Results: The Mean±SD age of the pregnant women with preeclampsia was 31.19±6.42 years with an interquartile interval of 26-35 years. History of preeclampsia (P=0.02), hypertension (P=0.001), and body mass index (P=0.001) were significantly higher in the preeclampsia group than in the control group. Also, there was no significant relationship between a history of diabetes mellitus, infertility, or twin with preeclampsia (P<0.05). Conclusion: This study showed that the risk factors of a history of preeclampsia, hypertension, and body mass index significantly differed between the case and control groups.
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