艾滋病毒感染人群中的COVID-19

IF 0.3 Q4 INFECTIOUS DISEASES HIV & AIDS Review Pub Date : 2021-01-01 DOI:10.5114/hivar.2021.111534
D. Daniella, Alfred Setyono, Marianto Marianto
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引用次数: 0

摘要

2019年新型冠状病毒病COVID-19已于2020年3月11日宣布为大流行。2019冠状病毒病的破坏性影响波及全球各行各业和个人。迄今为止,除了对症治疗或实验性治疗外,尚未发现明确和特异性的治疗方法。患有慢性疾病合并症的个体被认为具有更差的结果和更大的死亡风险。此外,某些慢性传染病,如人类免疫缺陷病毒(HIV),也被纳入COVID-19的影响个体,但影响程度未知。最近的各种研究表明,艾滋病毒感染者中没有更高的COVID-19风险,但受试者有限。此外,关于COVID-19在艾滋病毒感染人群中的结果以及抗逆转录病毒治疗(ART)在COVID-19中的作用仍然存在争议。在此背景下,与COVID-19大流行有关的另一个问题阻碍了艾滋病毒患者获得医疗服务并扰乱了抗逆转录病毒治疗的依从性,进一步增加了COVID-19致命发病率和死亡率的风险。由于COVID-19大流行的紧迫性,以及HIV的慢性、死亡率和大量感染,临床医生应该意识到HIV感染与COVID-19的关系。这篇综述文章总结了大流行期间艾滋病毒感染与COVID-19之间的关系,包括目前抗逆转录病毒治疗COVID-19的证据。
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COVID-19 among HIV-infected population
Novel coronavirus disease 2019, COVID-19, has been declared as a pandemic on March 11th, 2020. The devastating impact of COVID-19 has affected every sectors and individuals worldwide. No definite and specific treatment has been discovered up till now, apart from symptomatic or experimental treatments. Individuals with chronic disease comorbidity are identified to have worse outcomes and greater risk of mortality. Moreover, certain chronic infectious disease, such as human immunodeficiency virus (HIV), is also included as affected individuals by COVID-19 with unknown extent. Various recent studies suggested that there is no higher risk of COVID-19 among HIV-infected population, but subjects are limited. Additionally, controversies still exist regarding the outcome of COVID-19 in HIVinfected population as well as the role of antiretroviral therapy (ART) in COVID-19. Another problems regarding COVID-19 pandemic in this context impede medical access and disturb adherence to ART in HIV patients, further increasing risk of lethal morbidity and mortality of COVID-19. Because of the urgency of COVID-19 pandemic as well as chronicity, mortality, and great number of HIV infections, clinicians should be aware of the relationship between HIV infection and COVID-19. This review article summarized the association between HIV infection and COVID-19 during the pandemic, including the current evidence of ART in COVID-19.
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来源期刊
HIV & AIDS Review
HIV & AIDS Review INFECTIOUS DISEASES-
CiteScore
0.50
自引率
0.00%
发文量
30
审稿时长
12 weeks
期刊最新文献
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