COVID-19感染对男性生育能力的影响:一个叙事回顾

Elahe Taqvaee, Mohammadjavad Hesam, Ali Hajeb, Amir Norouzi Apourvari, Masoomeh Latifi, S. Fallahi
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摘要

一种新的冠状病毒的出现,正式名称为严重急性呼吸系统综合征冠状病毒2 (SARS-CoV-2),给全世界所有医护人员和临床医生带来了挑战。这种病毒在包括精液在内的生物体液中的存在引起了人们对不孕症治疗的一些担忧。有证据表明,导致2019冠状病毒病(COVID-19)的SARS-CoV-2可以在细胞因子风暴引起的炎症过程后损害男性生殖系统。然而,SARS-CoV-2对生育能力和人类睾丸生殖能力的直接和长期影响仍存在争议。即使在完全康复后,病毒的持续存在也会增加性传播的风险,并对男性生殖系统、性功能和生育能力产生不利影响。因此,有必要仔细评估男性患者的生殖器官和睾丸功能。本研究旨在评估SARS-CoV-2对睾丸和男性生殖的侵袭作用。
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The Effect of COVID-19 Infection on Male Fertility: A Narrative Review
The emergence of a new coronavirus, officially referred to as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 ), has challenged all healthcare workers and clinicians worldwide. The presence of the virus in biological fluids including the semen has raised some concerns about infertility treatment. There is evidence that SARS-CoV-2, which causes coronavirus disease 2019 (COVID-19), can damage the male reproductive system following the inflammatory process caused by the cytokine storm. However, the direct and long-term effects of SARS-CoV-2 on fertility and the reproductive capacity of the human testis are still open to controversy. The lasting presence of the virus, even after a complete recovery, can increase the risk of sexual transmission and adversely affect the male reproductive system, sexual function, and fertility. Therefore, there is a need for a careful assessment of reproductive organs and testicular function in male patients. This study aimed to evaluate the invasive effect of SARS-CoV-2 on the testis and male reproduction.
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