生物传感器在癌症检测中的应用综述

Norhaniza Emrizal, Zainiharyati Mohd Zain, Khor Goot Heah
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引用次数: 0

摘要

如果癌症能及早发现,治愈的可能性就会更高。然而,由于诊断较晚,许多恶性肿瘤在扩散到全身后才被诊断出来。目前的设备在检测早期癌细胞方面存在局限性,因为信号的巨大变化限制了可重复性和灵敏度。因此,迫切需要更特异、更灵敏的生物传感器装置来进行早期癌细胞检测。近年来,由于生物传感器在癌症检测中的广泛应用,生物传感器技术的设计和发展成为人们关注的焦点。这些装置将基因组物质转换成电信号,可以通过识别特定的生物分析物来识别。此外,近年来生物传感器与纳米材料的结合应用为癌症监测和检测提供了一种极好的策略。本文综述了近年来生物传感器在生物识别方面的研究进展。最后,本文重点介绍了纳米材料和微技术在生物传感器检测各种癌症方面的最新进展。
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The biosensor application in cancer detections: A review
Cancer has a higher possibility to be cured if the cancer can be detected earlier. However, many malignancies are currently diagnosed only after they have spread throughout the body due to late diagnosis. Current devices have limitations to detect early cancer cells as the huge variations in the signal and limiting repeatability and sensitivity. Thus, more specific, and sensitive device of biosensor is required urgently for early cancer cells detection. The design and advancement of biosensor technology has become a focal point in recent years due to a broad variety of biosensor applications of cancer detections. These devices convert the genomic materials into an electric signal that can be identified by recognizing a specific biological analyte. In addition, the recent application of biosensors together with nanomaterials has constituted an excellent strategy in cancer monitoring and detection. This review recaps the latest literature search insights the biosensors development and application on their biological recognitions. Finally, the up-to-date approaches applied in biosensors using the nanomaterials and micro-technologies as advancement in detecting various cancers are highlighted in this review paper.
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来源期刊
Asia-pacific Journal of Molecular Biology and Biotechnology
Asia-pacific Journal of Molecular Biology and Biotechnology Biochemistry, Genetics and Molecular Biology-Biotechnology
CiteScore
0.90
自引率
0.00%
发文量
25
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