{"title":"泛素-蛋白酶体系统在非小细胞肺癌中的潜在机制","authors":"Yuxiu Wang","doi":"10.3760/CMA.J.ISSN.1673-436X.2020.04.008","DOIUrl":null,"url":null,"abstract":"The ubiquitin-proteinasome system (UPS) is a complex control system responsible for the degradation of 80%-90% of proteins and is the key to regulating cellular function and maintaining protein homology.Studies have shown that it plays an important role in the development of a variety of tumors.Therefore, the component of UPS has attracted extensive attention as a potential target for the diagnosis and treatment of lung cancer in recent years.This article reviews the research status of UPS in non-small cell lung cancer and its potential mechanism in the development of non-small cell lung cancer. \n \n \nKey words: \nCarcinoma, non-small-cell lung; Ubquitin-proteinasome system; Mechanism","PeriodicalId":10004,"journal":{"name":"Chinese Journal of Asthma","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2020-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The potential mechanism of ubiquitin-proteasome system in non-small cell lung cancer\",\"authors\":\"Yuxiu Wang\",\"doi\":\"10.3760/CMA.J.ISSN.1673-436X.2020.04.008\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The ubiquitin-proteinasome system (UPS) is a complex control system responsible for the degradation of 80%-90% of proteins and is the key to regulating cellular function and maintaining protein homology.Studies have shown that it plays an important role in the development of a variety of tumors.Therefore, the component of UPS has attracted extensive attention as a potential target for the diagnosis and treatment of lung cancer in recent years.This article reviews the research status of UPS in non-small cell lung cancer and its potential mechanism in the development of non-small cell lung cancer. \\n \\n \\nKey words: \\nCarcinoma, non-small-cell lung; Ubquitin-proteinasome system; Mechanism\",\"PeriodicalId\":10004,\"journal\":{\"name\":\"Chinese Journal of Asthma\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2020-02-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Chinese Journal of Asthma\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.3760/CMA.J.ISSN.1673-436X.2020.04.008\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Chinese Journal of Asthma","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3760/CMA.J.ISSN.1673-436X.2020.04.008","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
The potential mechanism of ubiquitin-proteasome system in non-small cell lung cancer
The ubiquitin-proteinasome system (UPS) is a complex control system responsible for the degradation of 80%-90% of proteins and is the key to regulating cellular function and maintaining protein homology.Studies have shown that it plays an important role in the development of a variety of tumors.Therefore, the component of UPS has attracted extensive attention as a potential target for the diagnosis and treatment of lung cancer in recent years.This article reviews the research status of UPS in non-small cell lung cancer and its potential mechanism in the development of non-small cell lung cancer.
Key words:
Carcinoma, non-small-cell lung; Ubquitin-proteinasome system; Mechanism
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