PIC法制备低粘度W/O纳米乳的稳定性研究

W. Cho
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引用次数: 1

摘要

本研究采用PIC法在高温下制备了水/Span 80-Nikkol bl25 /油体系的W/O纳米乳液。该方法可以在该体系中形成分散良好的低粘度W/O纳米乳液。然而,在室温下,PIC法制备的是大乳液,而不是纳米乳液。由于界面张力随温度的显著变化,在30℃至80℃温度范围内,随着温度的升高,乳状液滴尺寸从2µm减小到100 nm。在80℃条件下制备的纳米乳液的液滴尺寸在50 ~ 200 nm范围内,内相含量可高达15 wt%。在乳化剂混合物的最佳HLB值为7.0附近形成了最稳定的纳米乳。所制得的纳米乳在1个月内稳定,液滴大小无明显变化。该研究为优化低粘度水/水纳米乳的形成提供了有价值的信息。这些结果表明,低粘度的W/O纳米乳液可以用于具有柔软感觉的化妆品。
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Stability of W/O Nanoemulsions with Low Viscosity Prepared by PIC Method
: In this study, water-in-oil (W/O) nanoemulsions of water/Span 80-Nikkol BL 25/oil system were prepared by the PIC method at elevated temperature. This method allows the formation of finely dispersed W/O nanoemulsions with low viscosity in this system. However, macroemulsions rather than nanoemulsions were prepared by PIC method at room temperature. As a result of the significant change of interfacial tension with temperature, the emulsion droplet size de-creases from 2 µ m to 100 nm with the increase in temperature from 30 ℃ to 80 ℃ . The droplet size of nanoemulsions prepared at 80 ℃ was in the range of 50 ∼ 200 nm and the internal phase content could reach as high as 15 wt%. The most stable nanoemulsion was formed in the vicinity of 7.0 of optimum HLB of the emulsifier mixture. The ob-tained nanoemulsions were stable without obvious change in droplet size in one month. This study provides valuable information for optimizing the formation of W/O nanoemulsions with low viscosity. These results suggest that W/O nanoemulsions of low viscosity could be useful for cosmetics with soft feeling.
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