Long term changes in biometric parameters of eye with primary angle closure suspect after laser peripheral iridotomy

Objective To quantitatively evaluate the long-term changes in biometric characteristics parameters after laser peripheral iridotomy (LPI) in primary angle closure suspect (PACS). Methods A prospective case series study. 40 PACS patients in Handan Eye Hospital, Hebei were enrolled in five years. LPI was performed in one eye selected randomly of every case (LPI group) , the other was as naturally control eye. Routine ophthalmic tests and A-scan examination were performed on both eyes at presentation、1 year and 5 year after LPI, including central anterior chamber depth (CACD),lens thickness (LT) and axial length (AL). Results Compared to before LPI, CACD was significantly deeper at 1 year, but more shallow at 5 year (all P<0.05). CACD in LPI group was more deeper than that in control group at 1 year, 5 year (P<0.05) . Within 5 years, CACD was grad-ually decreased, but the CACD at 5 year in the laser group was still bigger than that in the control group (P<0.05). LT in both team were thick gradually within 5 years (P<0.05) . Conclusions LPI can significantly deepen the central anterior chamber and delay the central anterior chamber shallow in PACS. Key words: primary angle closure suspect; laser peripheral iridotomy; lens