Registro Nacional de Actividad-Registro de la Sociedad Española de Fertilidad de fecundación in vitro e inyección espermática intracitoplasmática. Años 2014 y 2015

Introduction

This document presents the IVF/ICSI activity records of the National Activity Register-Spanish Fertility Society Register for the years 2014-2015. These were the first two years of mandatory participation in this Register for assisted reproduction centres in Spain.

Material and methods

The data analysed corresponded to the cycles carried out in 225 Spanish centres in 2014, and in 231 in 2015. The following IVF/ICSI cycles were studied: with own fresh oocytes, 51,591 in 2014 and 53,679 in 2015; with fresh donor oocytes, 16,630 in 2014 and 14,655 in 2015. Cycles with embryo cryopreservation totalled 21,007 in 2014 and 23,692 in 2015. PGD/PGS cycles totalled 5,242 in 2014 and 7,045 in 2015, and cycles with cryopreserved oocytes, 6,692 in 2014 and 8,138 in 2015.

Results

In IVF/ICSI with own fresh oocytes, a total of 12,576 clinical gestations were obtained in 2014 and 12,041 in 2015, representing pregnancy rates by fresh embryo transfer of 36.6% and 36.4%, respectively. Of these pregnancies, 21.3% were multiple in 2014 and 20.8% in 2015. In IVF/ICSI with fresh donor oocytes, 13,083 fresh transfers were performed in 2014 and 12,211 in 2015, which in 2014 resulted in 7,275 clinical gestations (55.6%) of which 28.1% were multiple, and in 2015 resulted in 6,653 (54.5%) of which 25.7% were multiple. In 2014, of the 1,689 transfers for PGD, 776 gestations were obtained (45.9%) and in 2015, of the 1,935 transfers, 917 gestations were obtained (47.4%). In 2014, 641 transfers were made with embryos from vitrified own oocytes and 5,372 with vitrified donated oocytes. In 2015, the corresponding figures were 712 and 6,416.

Conclusions

The number of cycles recorded has increased significantly, due to legislative changes that make participation in this Register mandatory. Particularly notable is the increase in donor cycles with vitrified oocytes. The rate of multiple gestation remains high.