尼日利亚埃邦伊州ISHIELU地方政府区血红梭菌患者尿液中的氨基酸动态

Hope Chinwe Achime, F. Okafor
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引用次数: 0

摘要

本文研究了血血吸虫患者尿液中氨基酸的动态变化,探讨了利用高感染、轻感染和未感染尿液中氨基酸模式作为快速筛查血吸虫病的诊断工具的可行性和有效性。本研究中采用的色谱方法显示尿样品中存在9种必需氨基酸和7种非必需氨基酸。结果表明,所有尿样均不含组氨酸、谷氨酰胺、丝氨酸和脯氨酸。此外,两种标记氨基酸的存在可用于识别重度感染(半胱氨酸)和未感染(蛋氨酸)的个体。关键词:氨基酸;快速诊断;血吸虫病
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AMINO ACID DYNAMICS IN URINE OF S. haematobium PATIENTS IN ISHIELU LOCAL GOVERNMENT AREA OF EBONYI STATE, NIGERIA
The Amino acid dynamics in urine samples of Schistosoma haematobium patients were studied The study was to evaluate the possibility and validity of using amino acid patterns recorded in highly, lightly and uninfected urines as diagnostic tool for rapid screening of Schistosomiasis Paper chromatography was used to separate the different amino acids in the urine samples. The chromatographic method used in this study revealed the existence of 9 essential and 7 nonessential amino acids in the urine samples. It equally showed that histidine, glutamine, serine and proline were absent in all the urine samples. Furthermore the presence of two marker amino acids can be used to identify individuals with heavy infection (cystein) and no infection (methionine). Keywords: Amino acids, Rapid diagnosis, Schistosomiasis, S. haematobium , Ebonyi State
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