色素性干皮病并发鳞状细胞癌及基底细胞癌1例

S. Venugopal, A. Muralidhar, Hemalata Mahantappa, Sadaf Ahmad
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引用次数: 0

摘要

着色性干皮病是一种遗传的DNA修复疾病,其特征是有缺陷的核苷酸切除修复,涉及修复紫外线诱导的锥体残基交联。受影响的个体在比正常年龄早得多的时候患皮肤粘膜癌的风险增加。这种遗传性皮肤病影响男女和所有种族。印度的发病率尚不清楚。我们报告一个这样的情况下,九岁的男孩与共存的鳞状细胞癌和基底细胞癌的脸。
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Rare occurrence of coexistent squamous cell carcinoma and basal cell carcinoma in a case of Xeroderma Pigmentosum
Xeroderma Pigmentosum is an inherited disorder of DNA repair characterised by defective nucleotide excision repair, which is involved in repairing ultraviolet rays induced cross linking of pyramidine residues. Affected individuals are at increased risk of development of mucocutaneous cancers at a much earlier age than normal. This genodermatosis affects both sexes and all races. The incidence in India is still unknown. We report one such case of a nine year old boy with co-existent squamous cell carcinoma and basal cell carcinoma of the face.
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