新型冠状病毒治疗药物活性基团的化学和机械作用

Suhayla K. Mohammed, Mzahim M. Taha, E. M. Taha
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摘要

随着新型冠状病毒病(COVID-19)新一轮全球疫情的爆发,控制和治疗变得至关重要。根据世界卫生组织(世卫组织)的报告,目前还没有药物被证明对治疗COVID-19引起的严重急性呼吸系统综合征有效。在这段时间进行的大多数研究都是临床试验。这些研究使用了洛匹那韦、利托那韦、雾化干扰素和氨基喹啉等几种药物。到目前为止,其作用机制还不清楚。本文根据力学标准研究了被试药物与不同类型合并蛋白的病毒膜的代谢产物。
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Chemical and Mechanical Actions of Drugs Active Group Used in COVID-19 Treatment
With the new global outbreak of the novel COVID-19, control and treatment has become critical. There is no medication proven to be effective for the treatment of severe acute respiratory syndrome which is caused by COVID-19 according to the World Health Organization (WHO) reports. Most studies that have been done on this time are clinical trials. Those studies used several drugs like lopinavir, ritonavir, nebulized alpha-interferon and, aminoquinolines. The mechanism of action is not well known so far. This review studies the metabolites of the tested drugs with different kinds of the viral membrane which merging proteins based on mechanical criteria.
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