2型糖尿病和基因治疗——CRISPR基因治疗2型糖尿病的前景

S. Khan
{"title":"2型糖尿病和基因治疗——CRISPR基因治疗2型糖尿病的前景","authors":"S. Khan","doi":"10.17352/2455-8583.000038","DOIUrl":null,"url":null,"abstract":"Gene therapy has entered a new era with the dawn of CRISPR/Cas9 technology which though \nwere always available in nature but rediscovered to tame into a real-tlife genome editing tool. With the \nmodernization upsurge and changes in ways the “homo sapiens” survived on this planet from hunger to \ncurrent era of exuberance has led to multiple metabolic issues like type-2 diabetes. Notwithstanding the \nrapid emergence of medication to suppress the hyperglycemia and insulin resistance associated with this \nmenace, need has defi nitely emerge to fi nd more personalized and curative dimensions to therapeutics \nof type-2 diabetes mellitus.","PeriodicalId":73168,"journal":{"name":"Global journal of obesity, diabetes and metabolic syndrome","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2019-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":"{\"title\":\"Type-2 diabetes and gene therapy- The promise of CRISPR gene therapy in type-2 diabetes mellitus\",\"authors\":\"S. Khan\",\"doi\":\"10.17352/2455-8583.000038\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Gene therapy has entered a new era with the dawn of CRISPR/Cas9 technology which though \\nwere always available in nature but rediscovered to tame into a real-tlife genome editing tool. With the \\nmodernization upsurge and changes in ways the “homo sapiens” survived on this planet from hunger to \\ncurrent era of exuberance has led to multiple metabolic issues like type-2 diabetes. Notwithstanding the \\nrapid emergence of medication to suppress the hyperglycemia and insulin resistance associated with this \\nmenace, need has defi nitely emerge to fi nd more personalized and curative dimensions to therapeutics \\nof type-2 diabetes mellitus.\",\"PeriodicalId\":73168,\"journal\":{\"name\":\"Global journal of obesity, diabetes and metabolic syndrome\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2019-07-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Global journal of obesity, diabetes and metabolic syndrome\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.17352/2455-8583.000038\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Global journal of obesity, diabetes and metabolic syndrome","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.17352/2455-8583.000038","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 2

摘要

随着CRISPR/Cas9技术的出现,基因治疗进入了一个新时代。尽管CRISPR/Cas9技术在自然界中一直可用,但它被重新发现,并被驯服为现实生活中的基因组编辑工具。随着现代化的高涨和“智人”在这个星球上生存方式的变化,从饥饿到现在的繁荣时代,导致了多种代谢问题,如2型糖尿病。尽管抑制与这种威胁相关的高血糖和胰岛素抵抗的药物迅速出现,但对于2型糖尿病的治疗方法,肯定需要找到更加个性化和治疗性的方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Type-2 diabetes and gene therapy- The promise of CRISPR gene therapy in type-2 diabetes mellitus
Gene therapy has entered a new era with the dawn of CRISPR/Cas9 technology which though were always available in nature but rediscovered to tame into a real-tlife genome editing tool. With the modernization upsurge and changes in ways the “homo sapiens” survived on this planet from hunger to current era of exuberance has led to multiple metabolic issues like type-2 diabetes. Notwithstanding the rapid emergence of medication to suppress the hyperglycemia and insulin resistance associated with this menace, need has defi nitely emerge to fi nd more personalized and curative dimensions to therapeutics of type-2 diabetes mellitus.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
期刊最新文献
Low CD4+ T Cell count among HIV-seronegative Type 2 Diabetes Mellitus patients in Ilorin metropolis Enhancing insulin supply chain resilience: A critical importance for diabetes management A rare and challenging case of ROHHAD (Rapid-onset Obesity with Hypoventilation, Hypothalamic Dysfunction, Autonomic Dysregulation) syndrome Benefits of omega-3 polyunsaturated fatty acids to patients with oral and metabolic diseases The period of manifestation of type 1 diabetes mellitus in children and adolescents living on the territory of ZATO (Closed administrative-territorial entity)
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1