DYNAMICS OF ENTEROBACTERIA ISOLATION IN PERIPROSTHETIC INFECTIONS

Implant-associated inflammation remains one of the main problems of unsatisfactory results of arthroplasty, which is characterized by the formation of a microbial biofilm on the surface of metal structures of various localization in orthopedics. Let us consider the family Enterobacteriaceae, the most frequently encountered microorganisms with high resistance to the different groups and types of antibiotics, and which form a biofilm on the surface of metal structures. The aim of the study is to study the frequency of occurrence of the Enterobacteriaceae family in patients with periprosthetic infections. All patients admitted with periprosthetic infection were studied. The biomaterial was studied by a special method to detect periprosthetic infection. Results in four years in total, 1750 bioassays were examined to detect this infection, during this period 27 types of microorganisms were identified in patients. The frequency of isolation of the family Enterobacteriaceae among all isolated microorganisms is 26.1%. In the dynamics of the observed period in this group of microorganisms, there was a change in pathogens from less resistant to more resistant ones. The analysis of studies on the identification of the Enterobacteriaceae family in periprosthetic infection suggests an increase in the number of isolated resistant strains of Acinetobacter spp. in four years by 12.3 times, the possible cause of which was Coronavirus infection (COVID-19).