一些新型恶西平衍生物的合成及理化性质

L. Joseph, M. George, Surekha
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摘要

以氨基脲为原料,以希夫斯碱为醛类衍生物合成了一系列恶氮平衍生物。然后等量的希夫斯碱与邻苯二酸酐或丁二酸酐在有机溶剂苯的存在下进行环加成反应,得到恶氮平环体系。根据光谱数据确定了合成化合物的化学结构
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Synthesis and physico-chemical characterization of some novel oxazepine derivatives
Series of oxazepine derivatives were synthesized from Schiffs base as aldehyde derivatives by using semicarbazide as starting material.Then equimolar quantities of prepared Schiffs base reacts with pthallic anhydride or succinic anhydride undergo cycloaddition reaction in the presence of organic solvent benzene give an oxazepine ring system. Chemical structures of the synthesized compounds were confirmed on the basis of their spectral data
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