PROCESS VALIDATION AND GC ANALYSIS OF PATHADISURA, A FERMENTED AYURVEDIC PRODUCT USED IN SHWAS VYADHI [BRONCHIAL ASTHMA]

Pathadisura [PS] is an ayurvedic fermented formulation, prescribed for respiratory disorders. It contains Suramanda prepared from (Rice grains), Guda (Jaggery) and herbal drugs viz Patha Murva, Rasna, Saral, Devdaru. The scientific preparation method and quality parameters of PS are not documented yet. Thus present study is aimed to develop and validate the preparation method and to generate quality standards for PS. Preparation of Sura, Suramanda and PS was done as per standard protocols of ayurvedic pharmaceutics blended with modern techniques. All herbal drugs, Sura and PS were tested with standard analytical methods. Obtained values for herbal drugs were within limits as per API standards, signify purity of plant materials. Study result provides organoleptic, physico-chemical values and gas chromatography quality standards for Sura and Pathadisura. Standard operating procedure for preparation of Sura and Pathadisura is developed and validated by using standard methods of analysis. It could be used in further studies. KEYWORDS: Pathadi Sura, Sura, Annamanda, Fermentation, GC Analysis.