儿童造血干细胞移植在塞尔维亚- 25年的经验

D. Vujic, Željko Zečević, Marija K Simic, B. Gobeljic, E. Lazic, G. Samardžija, O. Šerbić
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引用次数: 0

摘要

塞尔维亚母亲和儿童保健研究所的首例同种异体同胞供体造血干细胞移植。Vukan Cupic吗?(学院)是在上世纪七十年代演出的。大约20年后,首例来自兄弟姐妹单倍体捐赠者的异体移植手术在一名患有严重联合免疫缺陷的婴儿身上进行。经过几年的努力,骨髓移植科于1997年4月在该所开业。25年来,移植团队进行了360例造血干细胞移植,175例自体移植和185例异体移植(103例来自同卵兄弟供体,43例来自单倍体兄弟供体,36例来自匹配的非亲属供体,2例来自同卵兄弟脐带血,1例来自非亲属同卵脐带血)。
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Pediatric hematopoietic stem cell transplantation in Serbia - 25 years of experience
The first allogeneic identical sibling donor hematopoietic stem cell transplantation at the Institute for Mother and Child Health Care of Serbia ?Dr. Vukan Cupic? (Institute) was performed in the seventies of the last century. Almost twenty years later, the first allogeneic transplant from sibling haploidentical donor was performed in an infant suffering from severe combined immunodeficiency. After several years of efforts, the bone marrow transplant unit was opened in April 1997 at the Institute. Over the 25 years, the transplant team performed 360 hematopoietic stem cell transplantations, 175 autologous and 185 allogeneic (103 from identical sibling donor, 43 from haploidentical sibling donor, 36 from matched unrelated donor, 2 from identical sibling cord blood and 1 from unrelated identical cord blood).
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