113mIn螯合物- 1。一系列含113mIn烷基异二硫代氨基甲酸配合物的体外研究

Sonja Abram, Ulrich Abram, Hartmut Spies, Rudolf Münze
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引用次数: 6

摘要

通过与这些配体的水溶液反应,制备了7种铟二烷基二硫代氨基甲酸酯(R =乙基,n-丙基,i-丙基,正丁基,i-丁基,(CH2)5,(CH2)2O(CH2)2)。研究了不同浓度下的产物。用薄层色谱法、电泳法和辛醇/水分配法研究了低浓度下产物的性质。结果与表征良好的三(二烷基二硫代氨基甲酸)铟(III)配合物的行为进行了比较。
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113mIn chelate complexes—I. In vitro investigations on a series of alkylvaried dithiocarbamato complexes with 113mIn

A series of 7 indiumdialkyldithiocarbamates (R = ethyl, n-propyl, i-propyl, n-butyl, i-butyl, (CH2)5, (CH2)2O(CH2)2) has been prepared by reacting InCl3 with aqueous solutions of the ligands. The products have been investigated at various concentration levels. The properties of the products at the lower concentration levels have been studied by thin-layer chromatography, electrophoresis and by determination of the octanol/water partition. A comparison of the results with the behaviour of the well-characterized tris(dialkyldithiocarbamato)indium(III) complexes is given.

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