某综合专科医院老年患者多药及药物相关问题的发生率

T. Tamilselvan, T. Kumutha, M. Priyanka, R. Bose, M. Sindhuja
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引用次数: 6

摘要

http://dx.doi.org/10.21276/IJRDPL.22780238.2018.7(4).3055-3059摘要:本研究旨在评估老年患者使用多种药物及药物相关问题的发生率。这项前瞻性观察性研究在Vivekanandha医疗医院的150名老年患者中进行。采用Naranjo量表评估药物不良反应严重程度,采用BEER标准检查用药不当。65-70岁的老年患者使用多种药物的频率最高(65%)。大多数患者(43%)服用5-10种药物。在150例患者中,124例(83%)患者有合并症,26例(17%)患者无合并症。糖尿病和HTN患者的比例最高。主要是开抗高血压药。药物相互作用发生率以中度为主(59.50%)。评估DRP。62例中有119例药物重复。处方不当61例(101种药物)。34例患者共发生34例不良反应。从83个病例表中,确定了91个用药错误。药物相关问题在全科的发生率最高。全科老年人群多药及药物相关问题发生率较高。根据BEER的标准,苯二氮卓类药物是常用的不适当药物。本研究高度观察到可能的不良反应发生率。
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Incidence of Polypharmacy and Drug related problems among Geriatric patients in a Multispecialty hospital
http://dx.doi.org/10.21276/IJRDPL.22780238.2018.7(4).3055-3059 ABSTRACT:The study objectives were to assess the incidence of polypharmacy and drug-related problems among geriatric patients. This prospective, observational study was conducted in 150 geriatric patients at Vivekanandha medical care hospital. The severities of adverse drug reactions were assessed using Naranjo scale and inappropriate medications were examined using BEER’s criteria. The highest frequency of geriatric patients with polypharmacy was from the age group of 65-70 years (65%). Most of the patients (43%) were taking 5-10 drugs. Out of 150 patients, 124(83%) patients had comorbidities and 26(17%) patients were found without comorbidity. The percentage of patients suffering from DM and HTN were found to be the highest. Antihypertensive was mostly prescribed. The major incidence of drug-drug interaction was found in the moderate category (59.50%). DRP's were assessed. The incidence of 119 drug duplications was found in 62 cases. Inappropriate prescription of drugs was found in 61 cases (101 medications). A total of 34 ADRs were found in 34 cases. From 83 case sheets, 91 medication errors were identified. The incidence of drug related problems was highest in the general medicine department. The incidence of polypharmacy and drug-related problems were high in geriatric population of general medicine department. Benzodiazepine class of drugs was the commonly prescribed inappropriate medication as per the BEER's criteria. The incidence of probable ADR was highly observed in this study.
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