阿萨姆柞蚕茧蛋白抗尿路感染的研究进展

R. Singh, M. Sarma, M. Basak, Ritismita Devi
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引用次数: 0

摘要

摘要:蚕丝是一种生物材料,是由蚕和蜘蛛形成的纤维中产生的具有优异力学性能的纤维蛋白。除了作为一种优良的生物材料外,由于其愈合性能和抗菌活性避免感染的优点,自过去几个世纪以来,它也被用作医疗手术中的缝合线。丝绸作为一种材料在现代医学的各个领域也取得了成功在这里,研究人员试图研究丝蛋白的抗菌特性及其作为抗尿路感染细菌的药物的潜在用途。本研究旨在分析蚕丝蛋白丝胶蛋白和丝素蛋白对尿路感染病原菌的影响及其在抗生素敏感性中的作用。结果表明,丝胶蛋白和丝素蛋白对引起尿路感染的细菌具有潜在的抑菌作用,经处理后效果显著。
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Characterization of Antheraea assamensis Cocoon Proteins as a Potential Candidate against Urinary Tract Infection
ABSTRACT: Silk is a biomaterial which is a fibrous protein with remarkable mechanical properties produced in fibre formed by silkworms and spiders. Apart from being a fine biomaterial, it has also been used since past few centuries as sutures in medical surgeries due to its advantages in healing properties and antimicrobial activity to avoid infection. Silk as a material has also been successful in various modern medical areas.1 Here the researchers attempt to study the antimicrobial properties of silk proteins and their potential utility as medicinal agents against the bacteria of the urinary tract infections. This study was done to analyse the affect of muga silk based protein sericin and fibroin on the pathogenic bacteria causing UTI and its role in antibiotic sensitivity. It was found that there was a potential in both the silk proteins (Sericin and fibroin) in its anti-microbial effects against the UTI causing bacteria and had formidable results when treated against them.
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