雷尼单抗单用与雷尼单抗联合靶向视网膜激光治疗视网膜分支静脉闭塞伴黄斑水肿的比较

Mohamed Abdelmoneem, Mohamed Sayed Saif, Mohamed Abd Elkalek
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引用次数: 0

摘要

背景:视网膜静脉阻塞是仅次于糖尿病视网膜病变的第二常见的视网膜血管疾病。视网膜静脉分支闭塞(BRVO)发生在视网膜静脉分支之一的闭塞。闭塞多发生在动静脉交叉处,多见于颞上视网膜静脉。患者和方法:本研究采用随机对照研究,分为2组,分别为27只眼(单独使用雷尼单抗)和27只眼(雷尼单抗联合靶向视网膜激光)。结果:FFA和OCT-Macula检测BRVO, OCT-Macula检测黄斑水肿。目前的结果显示,与雷尼单抗联合视网膜激光治疗相比,单用雷尼单抗治疗在改善视力和减少黄斑水肿(减少中央窝厚度)方面具有高度统计学意义,P值<0.001。
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Comparison of Ranibizumab alone versus Ranibizumab with Targeted Retinal Laser for Branch Retinal Vein Occlusion with Macular Oedema.
: Background: Retinal vein occlusion is the second most common retinal vascular disease after diabetic retinopathy. Branch retinal venous occlusion (BRVO) occurs the occlusion of one of the branches of the retinal vein. The occlusion occurs mostly at arteriovenous crossing and more frequent in upper temporal retinal veins. Patients and Methods: In the current study, randomized control study was conducted on 2 groups divided into 27 eyes (Ranibizumab alone), 27 eyes (Ranibizumab and Targeted retinal laser). Results: The BRVO is investigated by FFA and OCT-Macula and macular edema is measured by OCT-Macula. And the current result shows highly statistically significant improvement in visual acuity and reducing macular edema (decrease foveal thickness)with P value <0.001 in Ranibizumab alone compared with Ranibizumab and retinal laser.
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