IN SILICO ADMET PROFILING AND MOLECULAR DOCKING OF NOVEL SUBSTITUTED THIENO[3,2-d] PYRIMIDINES AGAINST LIGAND BINDING DOMAIN OF THE HUMAN PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA IN COMPLEX WITH SYNTHETIC AGONIST

Pyrimidine ring system has wide range of pharmacological activities in the form of substituted and fused ring system and its derivatives. In this study we use some new computational tools for predicting ADMET, Pharmacological profile and Molecular docking of some novel substituted Thieno[3,2-d]pyrimidine. The side effect during the investigation is Carcinogenicity, Hepatotoxicity, etc., Molecular docking by using QSAR Software (Drug-receptor Interaction) it also focuses.