STATUS AND TRENDS OF THE EPIDEMIC SITUATION OF GROUP A STREPTOCOCCAL (GAS) INFECTIONS IN RUSSIA IN RECENT YEARS

Aim. To study the main epidemiological manifestations of GAS infection in Russia and to assess the scale of the problem. Materials and methods. A retrospective epidemiological analysis of official statistical reporting data (f. 2, f. 12) about the incidence and prevalence of the most sig­ nificant forms of group A streptococcal infection in 2009 — 2016 was performed. Results. There was a slight decrease in the total incidence of GAS infection in the Russian Federation. On the average, 1.8 million people fell ill every year, of which 600,000 were children aged 0 — 14. There was no reliable trend in incidence of acute rheumatic fever (ARF) in 2009 — 2016 (2.0 per 100 000 population). The risk group is adolescents. The main proportion is adults (64%). In recent years the incidence of rheumatic heart disease (RHD) increases rate in the adult group. Compared with the previous period (1996 — 2007), the situation with the incidence of diseases of the skin and subcutaneous tissue and prevalence of kidney disease improved. Conclusion. The findings indicate a high prevalence of streptococcal infection in the country. Aim. The study of the prognosis of epidemiological and economic effects of pneumococcal vaccination in laboring males with various chronic diseases. Materials and methods. Within the predictive (Markov) model, based on the published data, assessment of 5-year horizon pneumo­ coccal vaccination of laboring males perceived effectiveness in reducing mortality, avoiding mor­ bidity and economic loss in the country had been processed. According to the official statistics in