X. Ni, Quanming Zhao, Xiao-yun Pan, Gang Zhao, Xingyuan Zhu, Liu-bao Ren, Jiong Yu, Baisheng Cai, Jiyang Tan, Jingyi Mi
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Biocompatibility of a magnesium coating on a titanium surface and its effects on BMSCs
ABSTRACT Surface modification can effectively improve the biological activity of Ti, which is currently a popular research topic. In this study, we applied plasma electrolytic oxidation (PEO) technology to prepare a porous Mg-TiO2 coating on the surface of a Ti sheet. Then, we observed the adhesion and proliferation of bone marrow mesenchymal stem cells (BMSCs) on the surface of the Mg-TiO2 coating. The results showed that the Mg-TiO2 coating had a porous structure, and there was a uniform distribution of Mg on the surface and in the pores of the coating. The porous Mg-TiO2 coating showed good cytocompatibility and no obvious cytotoxicity. Significantly more BMSCs adhered to and proliferated on its surface than on pure Ti (p < 0.05). In conclusion, a Mg-TiO2 coating with a good surface morphology and good biocompatibility and bioactivity was prepared on a Ti surface by plasma technology and may have potential for clinical applications.
期刊介绍：
Materials Technology: Advanced Performance Materials provides an international medium for the communication of progress in the field of functional materials (advanced materials in which composition, structure and surface are functionalised to confer specific, applications-oriented properties). The focus is on materials for biomedical, electronic, photonic and energy applications. Contributions should address the physical, chemical, or engineering sciences that underpin the design and application of these materials. The scientific and engineering aspects may include processing and structural characterisation from the micro- to nanoscale to achieve specific functionality.
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