伊拉克各制药公司抗菌活性的筛选

Ruaa M. Atallah, S. Al-Awadi, Elham A. Kalaf, Zainab J. Ghaneim, Maan A. Fahad
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摘要

抗菌剂是一种杀死微生物或阻止其生长的药剂。抗菌剂可以根据其功能分类,它可能是一种杀微生物剂,是一种杀死微生物的药物,而那些只阻止和阻止微生物生长的药物被称为生物抑制剂。抗菌素耐药性(Antimicrobial resistance, AMR)是指微生物抵抗抗菌药物作用的能力,这些药物曾经可以通过杀死或阻止微生物的生长来成功地治疗微生物。因此,随着抗生素耐药性的日益普遍和世界范围内的出现,需要对抗生素的抗菌活性进行筛选。因此在本研究中,我们采用了许多实验室都采用的评价方法,对从本地和国外公司获得的抗菌药物对标准微生物的活性进行了筛选,标准微生物包括以下(大肠杆菌、金黄色葡萄球菌、铜绿假单胞菌、白色念珠菌),致病菌包括(大肠杆菌、金黄色葡萄球菌),分别来自肾脏感染和组织烧伤。总之,结果表明,伊拉克当地Al-Razi公司生产的抗生素比其他外国公司生产的抗生素效果更好,造成这种差异的原因可能是制造抗生素时使用的活性化学物质或制造方法不同。
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Screening of Antimicrobial Activity from Various Pharmaceutical Companies in Iraq
An antimicrobial is an agent that kills microorganisms or stops their growth. Antimicrobial can be classified according to their function, it may be a microbicidal which is an agent that kill microbes, while those that only prevent and stops their growth are named biostatic. Antimicrobial resistance (AMR) is the ability of a microbe to resist the effects of antimicrobial medication that once could successfully treat the microbe by killing or stop its growth. So with the resistance to the antibiotics becoming more and more common and worldwide resulting in need for screening the antimicrobial activity. So in this study we used an evaluation method which is used in many laboratories to screen the activity of antimicrobial agents obtained from a local company and a foreign company on standard microorganism which includes the following (Escherichia coli, staphylococcus aurous, Pseudomonas aeruginosa, Candida albicans) and pathogenic bacteria includes (Escherichia coli, staphylococcus aurous) which obtained from renal infections and tissue burns respectively.  In conclusion the results show that the antibiotic manufactured in the local company Al-Razi in Iraq gave better effectiveness than other foreign companies and the reason for this difference may due to the active chemicals used in manufacturing the antibiotic or due to the manufacturing method.
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