益康唑对人结直肠癌细胞Ca2+信号传导的影响

IF 0.6 4区生物学 Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY Turkish Journal of Biochemistry-turk Biyokimya Dergisi Pub Date : 2013-06-01 DOI:10.5505/TJB.2013.08370

Celia Carrillo, M. M. Cavia, S. Alonso-Torre

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引用次数: 1

摘要

简介:益康唑是一种广泛用作抗真菌药物的含唑化合物，目前正在研究其额外的治疗作用。事实上，econa- zole的抗肿瘤特性最近在体内和细胞水平上都得到了证实。然而，其作用背后的确切机制仍不清楚。目的:探讨益康唑对人腺癌细胞胞内Ca2+信号通路的影响。

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Effect of econazole on Ca2+ signaling in human colorectal adenocarcinoma cells

Introduction: Econazole, an azole compound widely used as an antifungal drug, is currently investigated for additional therapeutic effects. In fact, the antitumoral properties of econa- zole have been recently demonstrated, both in vivo and at the cellular level. However, the precise mechanism of action behind its effects is still unclear. Aim: To examine the effect of econazole on intracellular Ca2+ signaling pathways in a human adenocarcinoma cell line.

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来源期刊

Turkish Journal of Biochemistry-turk Biyokimya Dergisi 生物-生化与分子生物学

CiteScore

1.20

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： Turkish Journal of Biochemistry (TJB), official journal of Turkish Biochemical Society, is issued electronically every 2 months. The main aim of the journal is to support the research and publishing culture by ensuring that every published manuscript has an added value and thus providing international acceptance of the “readability” of the manuscripts published in the journal.