M. Fornari, A. Bava, M. Guereño, V. Berardi, M. R. Silaf, R. Negroni, R. Diez
{"title":"慢性副球孢子菌病患者血清白细胞介素-10和肿瘤坏死因子α水平升高","authors":"M. Fornari, A. Bava, M. Guereño, V. Berardi, M. R. Silaf, R. Negroni, R. Diez","doi":"10.1128/CDLI.8.5.1036-1038.2001","DOIUrl":null,"url":null,"abstract":"ABSTRACT In patients with chronic paracoccidioidomycosis (n= 10), levels of tumor necrosis factor alpha, interleukin-10, and interleukin-2 in serum, measured by enzyme-linked immunosorbent assay (in picograms per milliliter, as mean ± standard error of the mean), were higher than in normal controls (n = 8): 186 ± 40 versus 40 ± 7 (P < 0.05), 203 ± 95 versus 20 ± 8 (P = 0.001), and 96.3 ± 78.57 versus 1.19 ± 1.19 (P = 0.045), respectively. Gamma interferon and interleukin-4 levels were similar in patients and controls.","PeriodicalId":10395,"journal":{"name":"Clinical Diagnostic Laboratory Immunology","volume":"17 1","pages":"1036 - 1038"},"PeriodicalIF":0.0000,"publicationDate":"2001-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"33","resultStr":"{\"title\":\"High Serum Interleukin-10 and Tumor Necrosis Factor Alpha Levels in Chronic Paracoccidioidomycosis\",\"authors\":\"M. Fornari, A. Bava, M. Guereño, V. Berardi, M. R. Silaf, R. Negroni, R. Diez\",\"doi\":\"10.1128/CDLI.8.5.1036-1038.2001\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"ABSTRACT In patients with chronic paracoccidioidomycosis (n= 10), levels of tumor necrosis factor alpha, interleukin-10, and interleukin-2 in serum, measured by enzyme-linked immunosorbent assay (in picograms per milliliter, as mean ± standard error of the mean), were higher than in normal controls (n = 8): 186 ± 40 versus 40 ± 7 (P < 0.05), 203 ± 95 versus 20 ± 8 (P = 0.001), and 96.3 ± 78.57 versus 1.19 ± 1.19 (P = 0.045), respectively. Gamma interferon and interleukin-4 levels were similar in patients and controls.\",\"PeriodicalId\":10395,\"journal\":{\"name\":\"Clinical Diagnostic Laboratory Immunology\",\"volume\":\"17 1\",\"pages\":\"1036 - 1038\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2001-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"33\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical Diagnostic Laboratory Immunology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1128/CDLI.8.5.1036-1038.2001\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Diagnostic Laboratory Immunology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1128/CDLI.8.5.1036-1038.2001","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
High Serum Interleukin-10 and Tumor Necrosis Factor Alpha Levels in Chronic Paracoccidioidomycosis
ABSTRACT In patients with chronic paracoccidioidomycosis (n= 10), levels of tumor necrosis factor alpha, interleukin-10, and interleukin-2 in serum, measured by enzyme-linked immunosorbent assay (in picograms per milliliter, as mean ± standard error of the mean), were higher than in normal controls (n = 8): 186 ± 40 versus 40 ± 7 (P < 0.05), 203 ± 95 versus 20 ± 8 (P = 0.001), and 96.3 ± 78.57 versus 1.19 ± 1.19 (P = 0.045), respectively. Gamma interferon and interleukin-4 levels were similar in patients and controls.