口腔扁平苔藓的恶性转化——系统综述的总括性研究

S. Warnakulasuriya, P. Ramos-García, M. Gonzalez-Moles
{"title":"口腔扁平苔藓的恶性转化——系统综述的总括性研究","authors":"S. Warnakulasuriya, P. Ramos-García, M. Gonzalez-Moles","doi":"10.3390/oral3030024","DOIUrl":null,"url":null,"abstract":"Oral lichen planus (OLP) is classified as a potentially malignant disorder. Systematic reviews collating longitudinal observation studies provide evidence of the rate or proportion of malignant transformation. We conducted an umbrella study of published systematic reviews. An extensive English-language study search was carried out in several databases to identify relevant articles, providing systematic reviews on the malignant transformation of OLP. Data from eight systematic reviews published between 2014 and 2023 are presented. The reported proportions of malignant transformation ranged from 1.1% to 1.4%. A meta-analysis based on the 10 highest-quality studies yielded a higher proportion of malignant transformation (2.28%). We list some limitations found in several of these systematic reviews. Some studies reported an increased risk of malignancy in OLP lesions, demonstrating epithelial dysplasia. In view of the consistent evidence of the risk of oral malignancy, OLP patients should be monitored carefully to detect early cancer development.","PeriodicalId":19616,"journal":{"name":"Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics","volume":"63 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":"{\"title\":\"Malignant Transformation of Oral Lichen Planus—An Umbrella Study of Systematic Reviews\",\"authors\":\"S. Warnakulasuriya, P. Ramos-García, M. Gonzalez-Moles\",\"doi\":\"10.3390/oral3030024\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Oral lichen planus (OLP) is classified as a potentially malignant disorder. Systematic reviews collating longitudinal observation studies provide evidence of the rate or proportion of malignant transformation. We conducted an umbrella study of published systematic reviews. An extensive English-language study search was carried out in several databases to identify relevant articles, providing systematic reviews on the malignant transformation of OLP. Data from eight systematic reviews published between 2014 and 2023 are presented. The reported proportions of malignant transformation ranged from 1.1% to 1.4%. A meta-analysis based on the 10 highest-quality studies yielded a higher proportion of malignant transformation (2.28%). We list some limitations found in several of these systematic reviews. Some studies reported an increased risk of malignancy in OLP lesions, demonstrating epithelial dysplasia. In view of the consistent evidence of the risk of oral malignancy, OLP patients should be monitored carefully to detect early cancer development.\",\"PeriodicalId\":19616,\"journal\":{\"name\":\"Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics\",\"volume\":\"63 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-07-03\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.3390/oral3030024\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3390/oral3030024","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 2

摘要

口腔扁平苔藓(OLP)被列为一种潜在的恶性疾病。系统评价整理纵向观察研究提供了恶性转化率或比例的证据。我们对已发表的系统综述进行了概括性研究。在几个数据库中进行了广泛的英语研究检索,以确定相关文章,对OLP的恶性转化进行了系统的回顾。本文介绍了2014年至2023年间发表的8篇系统综述的数据。报道的恶性转化比例从1.1%到1.4%不等。基于10项最高质量研究的荟萃分析显示,恶性转化的比例更高(2.28%)。我们列出了在这些系统综述中发现的一些局限性。一些研究报道了OLP病变中恶性肿瘤的风险增加,表现为上皮发育不良。鉴于有一致的证据表明口腔恶性肿瘤的风险,OLP患者应仔细监测,以发现早期癌症发展。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Malignant Transformation of Oral Lichen Planus—An Umbrella Study of Systematic Reviews
Oral lichen planus (OLP) is classified as a potentially malignant disorder. Systematic reviews collating longitudinal observation studies provide evidence of the rate or proportion of malignant transformation. We conducted an umbrella study of published systematic reviews. An extensive English-language study search was carried out in several databases to identify relevant articles, providing systematic reviews on the malignant transformation of OLP. Data from eight systematic reviews published between 2014 and 2023 are presented. The reported proportions of malignant transformation ranged from 1.1% to 1.4%. A meta-analysis based on the 10 highest-quality studies yielded a higher proportion of malignant transformation (2.28%). We list some limitations found in several of these systematic reviews. Some studies reported an increased risk of malignancy in OLP lesions, demonstrating epithelial dysplasia. In view of the consistent evidence of the risk of oral malignancy, OLP patients should be monitored carefully to detect early cancer development.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
审稿时长
1 months
期刊最新文献
Real-Time Caries Detection of Bitewing Radiographs Using a Mobile Phone and an Artificial Neural Network: A Pilot Study Oral Cancer Disease among the Poor: A Sri Lankan Context Oro-Dental Pharmacovigilance in the Digital Age: Promoting Knowledge, Awareness, and Practice in Italy through a Smart Combined System—A Conference at the 30th National Congress of the Italian College of University Professors of Dental Disciplines Presurgical Decompensation in Patients Affected by Class III Dentoskeletal Malocclusion: A Comparison between Two Different Bracket Systems Corticotomy-Assisted Orthodontic Treatment: A Literature Review
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1