缺铁性贫血与埃及青少年体重的关系:一项横断面研究

M. S. M. RAGHDA A.MA. SELET, M.Sc., G. M. GHAFAGY, M.D.
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摘要

背景:肥胖和缺铁性贫血是两个全球性的健康问题,对人类健康造成重大影响。许多研究发现它们之间的关联可以通过慢性炎症介质来解释,即肥胖人员中影响铁吸收和运输的慢性炎症介质的增加。相反,其他研究否认了这种联系,尤其是在青少年中。研究目的:探讨埃及青少年肥胖与缺铁性贫血的关系。患者与方法:横断面研究纳入Kasr Al-Ainy医院家庭医学门诊就诊的127名14-19岁青少年。根据他们的体重指数,根据世界卫生组织的生长曲线,将他们分为正常体重、超重和肥胖。进行人口统计资料、病史和检查以确定纳入和排除标准。取血测定血红蛋白浓度和血清铁蛋白水平。结果:缺铁性贫血在正常人群中的发生率高于超重和肥胖人群(分别为64%、17.4%和18.6%)。这种差异非常显著。(p <0.001)。结论:缺铁性贫血在埃及青少年中很常见(127名参与者中有86名)。正常体重患者的贫血发生率高于肥胖患者,说明肥胖并非其他研究认为的青少年贫血发生的决定性因素。
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Iron Deficiency Anemia in Relation to Body Weight in Egyptian Adolescents: A Cross Sectional Study
Background: Obesity & iron deficiency anemia are two global health problems, with major consequences on human health. Many studies found an association between them explained by chronic inflammatory mediators that increase in obese personnel affecting iron absorption & transport. On the contrary, other studies denied this association especially in adolescents. Aim of Study: Assessment of the relation between obesity & iron deficiency anemia in Egyptian adolescents. Patients and Methods: Thecross sectional study included 127 adolescent participants aged 14-19 years old attending outpatient clinic for Family Medicine, Kasr Al-Ainy Hospital. They were classified according to their body mass indexinto normal weight, overweight & obese according to growth using WHO growth curves. Demographic data, medical history & examination were done to confirm inclusion & exclusion criteria. A blood sample was taken for hemoglobin concentra- tion & serum ferritin level. Results: Iron deficiency anemia was more prevalent in normal than in overweight & obese patients (64%, 17.4%, 18.6% respectively). The difference was highly significant. ( p <0.001). Conclusion: Iron deficiency anemia is common in Egyptian adolescents (86 out of 127 participants). The higher incidence of anemia in normal weight than obese patients denotes that obesity is not a decisive factor in development of anemia in adolescents as suggested by other studies.
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