COMPARATIVE STUDY OF SINENSETIN COMPOUND IN THE LEAVES OF ORTHOSIPHON STAMINEUS BENTH. FROM DIFFERENT REGIONS OF INDONESIA

The optimal growth of plant can be influenced by various factors, including the growing place. Because it could influenced the metabolites biosynthesis. This aimed study is to comparison the metabolite level, such as sinensetin of O. stamineus leaves from three regions in Indonesia (Tawangmangu, Batu and Trenggalek). The determination of sinensetin using TLC-densitometry with silica gel as solid phase and Chloroform-ethylaceate (60:40) as solvent system. The result showed the percentage of sinensetin in samples Tawangmangu, Batu and Trenggalek region were 0.04 ± 0.01; 0.07± 0.01 and 0.14 ± 0.01 respectively. It can be concluded that the best planting area that can produce fertile Orthosiphon stamineus with the highest content of sinensetin was in Trenggalek region. KEYWORD: Orthsiphon stamineus, Sinensetin, planting, regions INTRODUCTIONS Orthosiphon stamineus Benth of Lamiaceae family is a medicinal plant that widely grown in tropical areas. The plant can be identified by its white or purple colored flowers that resembles cat whiskers. It is also commonly referred as "Kumis Kucing" which means cat whiskers. The herb is popularly known as Java tea and is used widely in the form of herbal tea in Asia. [1] The leaves of this plant are used in traditional medicine as a diuretics, rheumatisme, urinary tract infection, kronic and acute kidney infection and billiary lithiasis. [2] There are many World Journal of Pharmaceutical Research SJIF Impact Factor 7.523 Volume 6, Issue 11, 96-102. Research Article ISSN 2277–7105 *Corresponding Author Dr. Sukardiman Departement of Pharmacognosy and Phytochemistry, Faculty of Pharmacy Universitas Airlangga, Surabaya, Indonesia. Article Received on 29 July 2017, Revised on 18 August 2017, Accepted on 07 Sep 2017 DOI: 10.20959/wjpr201711-9602