孟加拉国定制抗肝草药配方的定性评估

Md. Hafizur Rahman, B. Rokeya, M. Mosihuzzaman, Md. Shahinul Haque Khan
{"title":"孟加拉国定制抗肝草药配方的定性评估","authors":"Md. Hafizur Rahman, B. Rokeya, M. Mosihuzzaman, Md. Shahinul Haque Khan","doi":"10.3329/dujps.v21i1.60397","DOIUrl":null,"url":null,"abstract":"Qualitative assessment of herbal formulations is used in pre-health care of many diseases. The potency, composition and safety of herbal formulation are serious concerns in Bangladesh. Therefore, the aim of the present study was to evaluate the qualitative assessment of a customized anti-hepatic herbal formulation in Bangladesh. Isolation of compounds, toxic metals analysis, phytochemical screening, microbial test and determination of SGPT and SGOT level of hepatic model rats were focused in this study. The phytochemical screening revealed the presence of phenol, saponins and tannins. In chemical study, four known compounds were isolated from the formulation (Sodium benzoate, methyl-4-hydroxybenzoate, 4-hyroxybenzaldehyde and 4-hydroxy- 3-methoxybenzaldehyde). The results of microbial purity and toxic metals analysis were in favorable limit although the levels of SGOT and SGPT were raised non-significantly. So, based on the study it has been concluded that quality assessment is urgently required for this type of customized herbal formulations.\nDhaka Univ. J. Pharm. Sci. 21(1): 59-67, 2022 (June)","PeriodicalId":11304,"journal":{"name":"Dhaka University Journal of Pharmaceutical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2022-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Qualitative Assessment of a Customized Anti-hepatic Herbal Formulation in Bangladesh\",\"authors\":\"Md. Hafizur Rahman, B. Rokeya, M. Mosihuzzaman, Md. Shahinul Haque Khan\",\"doi\":\"10.3329/dujps.v21i1.60397\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Qualitative assessment of herbal formulations is used in pre-health care of many diseases. The potency, composition and safety of herbal formulation are serious concerns in Bangladesh. Therefore, the aim of the present study was to evaluate the qualitative assessment of a customized anti-hepatic herbal formulation in Bangladesh. Isolation of compounds, toxic metals analysis, phytochemical screening, microbial test and determination of SGPT and SGOT level of hepatic model rats were focused in this study. The phytochemical screening revealed the presence of phenol, saponins and tannins. In chemical study, four known compounds were isolated from the formulation (Sodium benzoate, methyl-4-hydroxybenzoate, 4-hyroxybenzaldehyde and 4-hydroxy- 3-methoxybenzaldehyde). The results of microbial purity and toxic metals analysis were in favorable limit although the levels of SGOT and SGPT were raised non-significantly. So, based on the study it has been concluded that quality assessment is urgently required for this type of customized herbal formulations.\\nDhaka Univ. J. Pharm. Sci. 21(1): 59-67, 2022 (June)\",\"PeriodicalId\":11304,\"journal\":{\"name\":\"Dhaka University Journal of Pharmaceutical Sciences\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-06-26\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Dhaka University Journal of Pharmaceutical Sciences\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.3329/dujps.v21i1.60397\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Dhaka University Journal of Pharmaceutical Sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3329/dujps.v21i1.60397","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1

摘要

草药配方的定性评估用于许多疾病的保健前。草药配方的效力、成分和安全性是孟加拉国严重关切的问题。因此,本研究的目的是评估孟加拉国定制抗肝草药配方的定性评估。本研究的重点是化合物的分离、有毒金属分析、植物化学筛选、微生物试验以及肝模型大鼠SGPT和SGOT水平的测定。植物化学筛选显示酚、皂苷和单宁的存在。在化学研究中,从该配方中分离到4个已知化合物(苯甲酸钠、4-羟基苯甲酸甲酯、4-羟基苯甲醛和4-羟基- 3-甲氧基苯甲醛)。微生物纯度和有毒金属分析结果良好,但SGOT和SGPT水平无显著升高。因此,在研究的基础上得出结论,迫切需要对这类定制草药配方进行质量评价。达卡大学药学院。科学21(1):59-67,2022 (6)
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Qualitative Assessment of a Customized Anti-hepatic Herbal Formulation in Bangladesh
Qualitative assessment of herbal formulations is used in pre-health care of many diseases. The potency, composition and safety of herbal formulation are serious concerns in Bangladesh. Therefore, the aim of the present study was to evaluate the qualitative assessment of a customized anti-hepatic herbal formulation in Bangladesh. Isolation of compounds, toxic metals analysis, phytochemical screening, microbial test and determination of SGPT and SGOT level of hepatic model rats were focused in this study. The phytochemical screening revealed the presence of phenol, saponins and tannins. In chemical study, four known compounds were isolated from the formulation (Sodium benzoate, methyl-4-hydroxybenzoate, 4-hyroxybenzaldehyde and 4-hydroxy- 3-methoxybenzaldehyde). The results of microbial purity and toxic metals analysis were in favorable limit although the levels of SGOT and SGPT were raised non-significantly. So, based on the study it has been concluded that quality assessment is urgently required for this type of customized herbal formulations. Dhaka Univ. J. Pharm. Sci. 21(1): 59-67, 2022 (June)
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
期刊最新文献
Design, Optimization and In vitro Evaluation of Mesalazine 400 mg Delayed Release Tablet for Colon Specific Delivery Formulation and Evaluation of Ledipasvir Nano-suspension Through QbD Approach Anti-viral Activity of 62 Medicinal Plants, Herbs and Spices Available in Bangladesh: A Mini Review In vitro and In vivo Interaction of Ketorolac Tromethamine and Cefixime Trihydrate Isolation and Characterization of Alkaline Proteases Producing Indigenous Bacillus sp. as a Source of Thrombolytic and Fibrinolytic Agents
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1