肝脏运输的定量活体显微镜观察

IntraVital Pub Date : 2012-07-01 DOI:10.4161/intv.21296
Clifford M. Babbey, Jennifer C Ryan, E. Gill, M. Ghabril, Courtney R. Burch, April Paulman, K. Dunn
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引用次数: 21

摘要

活体显微术在肝脏研究中有着悠久的应用历史。在这里,我们展示了活体多光子显微镜如何与数字图像分析相结合,定量评估药物对体内肝细胞运输的影响。
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Quantitative intravital microscopy of hepatic transport
Intravital microscopy has a long history of application to studies of the liver. Here we demonstrate how intravital multiphoton microscopy may be combined with digital image analysis to quantitatively evaluate the effects of drugs on hepatocyte transport in vivo.
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