影响迪拜和阿联酋北部心脏病医生处方态度的因素:一项横断面研究

Heba Jeroudy, M. Al-Tabakha, A. Ashames, A. Jairoun
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摘要

摘要背景不合理用药导致的不良事件日益引起人们的关注,需要对处方模式进行调查。对于心血管药物来说,这可能会增加患者患心脏病、中风和冠状动脉疾病的风险。这项研究特别考察了影响处方模式的心脏病专家行为。在阿拉伯联合酋长国(UAE),主要是在迪拜和北阿联酋的私立医院和诊所,调查了制药公司的促销活动和其他影响其处方的因素的影响。方法采用结构化问卷进行在线调查,确定在迪拜和北阿联酋工作的心脏病专家的样本量为59人,使用从可用的心脏病专家登记处随机生成的数字,并假设95%的置信度,回复率为80%。处方行为的评级使用原始的Bloom截断点,更新和调整以评估阿联酋心脏病专家的一般处方实践。结果平均处方行为评分为中等(76.5%);95%置信区间[CI], 75.1-77.8)。与北阿联酋相比,来自迪拜的心脏病专家的处方模式更好(优势比4.24;95% ci, 1.06-16.97)。制药公司赞助的继续医学教育是影响心内科医师改变处方的主要因素(96.6%)。共有40.7%的心脏病专家认为应该将处方从品牌药改为普通药,而43%的人表示,包括新研究证据在内的临床更新是影响他们开处方行为模式的其他因素之一。结论迪拜和阿联酋北部地区心脏病医生的处方行为高于平均水平,并且心脏病医生意识到接受昂贵礼物的不道德行为。迪拜和阿联酋北部的心脏病专家在采用一种新药物时被认为是合乎道德的,与其他地区进行的类似研究一致,因为他们的主要动机是患者的福利,这将有助于他们理性地选择药物。
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Factors Affecting the Cardiologists' Prescribing Attitudes in Dubai and the Northern Emirates: A Cross-sectional Study
Abstract Background  The growing concern of irrational drug use that leads to adverse events requires attention to investigate the prescription patterns. For cardiovascular drugs, this could increase patients' risk of developing a heart attack or stroke and coronary artery disease. This study particularly examines cardiologist behaviors that influence prescription patterns. The influence of pharmaceutical companies' promotions and other factors affecting their prescriptions in the United Arab Emirates (UAE), mainly in Dubai and the Northern Emirates private hospitals and clinics, were investigated. Methods  Online survey questions were undertaken using the structured questionnaire, and the determined sample size of the cardiologists working in Dubai and the Northern Emirates was 59 using randomly generated numbers from the available cardiologists' registry and assuming 95% confident with the 80% response rate. Ratings of the prescribing behavior were done using the original Bloom's cutoff points, which were updated and adjusted to evaluate UAE cardiologists' general prescribing practices. Results  The average prescribing behavior score was moderate (76.5%; 95% confidence interval [CI], 75.1–77.8). Better prescribing patterns were observed among the cardiologists from Dubai compared with the Northern Emirates (odds ratio 4.24; 95% CI, 1.06–16.97). Continued medical education sponsored by pharmaceutical companies was the main influential factor (96.6%) affecting the cardiologists in changing their prescription. A total of 40.7% of the cardiologists believed in changing the prescription from brand to generic, while 43% stated that clinical updates, including evidence from new studies, were among the other factors affecting their prescribing behavior pattern. Conclusion  The cardiologists' prescribing behaviors in Dubai and the Northern Emirates are above average and the cardiologists are aware of the unethical acceptance of pricey gifts. Cardiologists in Dubai and the Northern Emirates are considered ethical in adopting a new medication in agreement with similar studies conducted regionally, as their primary motivation is the welfare of patients, which will help them rationally select medication.
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