尼日利亚儿童川崎病1例报告

Sa Sotimehin, T. Ogunlesi, A. Adekanmbi, M. Fetuga, Ea Odumuyiwa, O. Olowu
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引用次数: 5

摘要

我们报告一个三岁的儿童,他在治疗发热性疾病期间出现药物引起的皮肤粘膜过敏反应,但最终在入院时表现出川崎病(KD)的所有诊断标准。虽然最初诊断为史蒂文-约翰逊综合征,但新出现的临床特征,血小板增多,低血浆蛋白和高ESR,促使诊断改变为川崎病。由于没有静脉注射免疫球蛋白和我们不愿使用阿司匹林,她接受了卧床休息和类固醇治疗。虽然她入院时未表现出任何心脏超声心动图特征,但出院两天后,一份不顾医嘱的口头尸检报告显示,她突然死亡,提示心脏可能受累。鉴于与非机构或延迟最终治疗相关的高死亡率风险,将KD添加到伴有皮肤粘膜病变的发热儿童的鉴别诊断列表中是重要的。关键字;非典型麻疹,川崎病,尼日利亚,死因推断
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Kawasaki Disease in A Nigerian Child- a case report
We report a three year old child who appeared to have a drug-induced muco-cutaneous hypersensitivity reaction during treatment for a febrile illness, but eventually manifested all the diagnostic criteria for Kawasaki Disease (KD) while on admission. Although an initial diagnosis of Steven-Johnson's Syndrome was made, the emerging clinical features, presence of thrombocytosis, low plasma proteins and high ESR, prompted a change of diagnosis to Kawasaki Disease. She received bed rest and steroid therapy due to the absence of Intravenous ImmunoglobulinGand our reluctance to use aspirin. Although she did not manifest any echocardiographic cardiac features while on admission, a verbal autopsy report of her sudden death two days after discharge against medical advice, suggested possible cardiac involvement. In view of the high mortality risk asscociated with non-institution or delay of definitive treatment, it is important to add KD to the list of differential diagnoses in febrile children with muco-cutaneous lesions.  Key words; Atypical measles, Kawasaki Disease, Nigeria, Verbal Autopsy
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