{"title":"胶体生物纳米抗癌药物的研究进展","authors":"R. Lavanya, S. A. John","doi":"10.7439/IJPR.V6I3.3154","DOIUrl":null,"url":null,"abstract":"The exploitation of bio (plant) materials for the biosynthesis of nanoparticles is considered a green technology as it does not involve any harmful chemicals. The present study reports the raw plant extraction and synthesis of gold (Au) nanoparticles from HAuCl4 using the powder of novel C. guianensis. The secondary metabolites were responsible for the reduction of gold metal to nano-sized Au nanoparticles. The 50% (IC50) value of cytotoxic activity was observed in 50 L concentration of sample and was enough to control the cancerous HeLa cells.","PeriodicalId":14194,"journal":{"name":"International Journal of Pharmacological Research","volume":"33 1","pages":"120-126"},"PeriodicalIF":0.0000,"publicationDate":"2016-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Development of colloidal bio-nano drug for anticancer studies\",\"authors\":\"R. Lavanya, S. A. John\",\"doi\":\"10.7439/IJPR.V6I3.3154\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The exploitation of bio (plant) materials for the biosynthesis of nanoparticles is considered a green technology as it does not involve any harmful chemicals. The present study reports the raw plant extraction and synthesis of gold (Au) nanoparticles from HAuCl4 using the powder of novel C. guianensis. The secondary metabolites were responsible for the reduction of gold metal to nano-sized Au nanoparticles. The 50% (IC50) value of cytotoxic activity was observed in 50 L concentration of sample and was enough to control the cancerous HeLa cells.\",\"PeriodicalId\":14194,\"journal\":{\"name\":\"International Journal of Pharmacological Research\",\"volume\":\"33 1\",\"pages\":\"120-126\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2016-03-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Journal of Pharmacological Research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.7439/IJPR.V6I3.3154\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Pharmacological Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.7439/IJPR.V6I3.3154","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Development of colloidal bio-nano drug for anticancer studies
The exploitation of bio (plant) materials for the biosynthesis of nanoparticles is considered a green technology as it does not involve any harmful chemicals. The present study reports the raw plant extraction and synthesis of gold (Au) nanoparticles from HAuCl4 using the powder of novel C. guianensis. The secondary metabolites were responsible for the reduction of gold metal to nano-sized Au nanoparticles. The 50% (IC50) value of cytotoxic activity was observed in 50 L concentration of sample and was enough to control the cancerous HeLa cells.
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