花青素对尿酸损伤的肾保护作用——以紫甘薯为例花青素

Q3 Pharmacology, Toxicology and Pharmaceutics Biomedical and Pharmacology Journal Pub Date : 2023-06-30 DOI:10.13005/bpj/2645
A. Mahendra, Made Jawi, N. Astawa, P. Astawa, Wayan Putu Sutirta-Yasa
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引用次数: 0

摘要

花青素是广泛存在于各种天然产物中的植物成分。紫甘薯(Ipomoea batatas L.)是花青素的重要来源,花青素是一类具有多种药用价值的类黄酮。花青素的药用价值之一是它们可以防止尿酸等应激源的有害影响。另一方面,高尿酸血症及其相关影响被认为是对人类健康的重大挑战。鉴于肾脏是处理尿酸的重要器官,且尿酸与肾脏疾病相关,本文将重点重新评估紫甘薯花青素作为抗尿酸相关病理生物学的肾保护剂的作用。对这些花青素作为肾保护剂的潜力进行了进一步的研究。
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Renoprotective Effects of Anthocyanins Against Uric AcidInstigated Injury: Mini Review with a Special Emphasis on Purple Sweet Potato (Ipomoea batatas L.) Anthocyanins
Anthocyanins are ubiquitous phytoconstituents found in a wide array of natural products. Purple sweet potato (Ipomoea batatas L.) is an important source of anthocyanins, a group of flavonoids with various medicinal benefits. One of the medicinal benefits of anthocyanins is their protection against the detrimental effects of stressors such as uric acid. On the other hand, hyperuricemia and its associated effects are considered significant challenges in human health. Since kidneys are essential organs in uric acid handling and uric acid is associated with kidney disease, this review focuses on re-appraising the role of purple sweet potato anthocyanins as renoprotectors against uric acid-related pathobiology. Future studies regarding the potential of these anthocyanins as renoprotectors are also discussed.
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来源期刊
Biomedical and Pharmacology Journal
Biomedical and Pharmacology Journal Pharmacology, Toxicology and Pharmaceutics-Pharmacology
CiteScore
1.20
自引率
0.00%
发文量
189
期刊介绍: Biomedical and Pharmacology Journal (BPJ) is an International Peer Reviewed Research Journal in English language whose frequency is quarterly. The journal seeks to promote research, exchange of scientific information, consideration of regulatory mechanisms that affect drug development and utilization, and medical education. BPJ take much care in making your article published without much delay with your kind cooperation and support. Research papers, review articles, short communications, news are welcomed provided they demonstrate new findings of relevance to the field as a whole. All articles will be peer-reviewed and will find a place in Biomedical and Pharmacology Journal based on the merit and innovativeness of the research work. BPJ hopes that Researchers, Research scholars, Academician, Industrialists etc. would make use of this journal for the development of science and technology. Topics of interest include, but are not limited to: Biochemistry Genetics Microbiology and virology Molecular, cellular and cancer biology Neurosciences Pharmacology Drug Discovery Cardiovascular Pharmacology Neuropharmacology Molecular & Cellular Mechanisms Immunology & Inflammation Pharmacy.
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