K. Shachi, N. Dubey, Sanjeev Kumar, N. K. Prasad, U. Dubey
{"title":"胡萝卜(Daucus carota Linn.)果汁代谢物治疗白化大鼠四氧嘧啶诱导的1型糖尿病的降糖、降血和降胆固醇作用","authors":"K. Shachi, N. Dubey, Sanjeev Kumar, N. K. Prasad, U. Dubey","doi":"10.15406/JDMDC.2020.07.00197","DOIUrl":null,"url":null,"abstract":"Introduction In present study an effort has been made to assess the hypoglycemic Anticholestrolemic and haematinic activity of carrot juice in alloxan monohydrate induced experimental animal model nbsp Materials and methods Rats were acclimatized for days in lab temperature All animals were given standard water and pellet diet Diabetes was induced in rats with the help of alloxan monohydrate mg kg body weight After alloxan monohydrate injection rats were separated and treatment started with carrot juice and insulin nbsp Results and discussion A marked rise in fasting blood glucose as well as serum cholesterol level was observed in diabetic control rats when compared to normal control rats Antihyperglycemic Anti cholesterolmic and haematinic activity observed in carrot juice administered rats on th th st and th days post treatment Anti hyperglycemic and anti cholesterol mic activity was found less effective than that of insulin treatment group nbsp Conclusion It is hope that present investigation will be helpful in establishing a scientific basis for antidiabetic haematinic and Anti cholesterolmic effects in experimental animal model The results are lt statistically significant","PeriodicalId":92240,"journal":{"name":"Journal of diabetes, metabolic disorders & control","volume":"18 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2020-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"3","resultStr":"{\"title\":\"Anti-diabetic, haematinic and anti-cholesterolmic effects of carrot (Daucus carota Linn.) juice metabolites to cure alloxan monohydrate induced type-1 diabetes in albino rats\",\"authors\":\"K. Shachi, N. Dubey, Sanjeev Kumar, N. K. Prasad, U. Dubey\",\"doi\":\"10.15406/JDMDC.2020.07.00197\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Introduction In present study an effort has been made to assess the hypoglycemic Anticholestrolemic and haematinic activity of carrot juice in alloxan monohydrate induced experimental animal model nbsp Materials and methods Rats were acclimatized for days in lab temperature All animals were given standard water and pellet diet Diabetes was induced in rats with the help of alloxan monohydrate mg kg body weight After alloxan monohydrate injection rats were separated and treatment started with carrot juice and insulin nbsp Results and discussion A marked rise in fasting blood glucose as well as serum cholesterol level was observed in diabetic control rats when compared to normal control rats Antihyperglycemic Anti cholesterolmic and haematinic activity observed in carrot juice administered rats on th th st and th days post treatment Anti hyperglycemic and anti cholesterol mic activity was found less effective than that of insulin treatment group nbsp Conclusion It is hope that present investigation will be helpful in establishing a scientific basis for antidiabetic haematinic and Anti cholesterolmic effects in experimental animal model The results are lt statistically significant\",\"PeriodicalId\":92240,\"journal\":{\"name\":\"Journal of diabetes, metabolic disorders & control\",\"volume\":\"18 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2020-05-11\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"3\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of diabetes, metabolic disorders & control\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.15406/JDMDC.2020.07.00197\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of diabetes, metabolic disorders & control","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15406/JDMDC.2020.07.00197","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Anti-diabetic, haematinic and anti-cholesterolmic effects of carrot (Daucus carota Linn.) juice metabolites to cure alloxan monohydrate induced type-1 diabetes in albino rats
Introduction In present study an effort has been made to assess the hypoglycemic Anticholestrolemic and haematinic activity of carrot juice in alloxan monohydrate induced experimental animal model nbsp Materials and methods Rats were acclimatized for days in lab temperature All animals were given standard water and pellet diet Diabetes was induced in rats with the help of alloxan monohydrate mg kg body weight After alloxan monohydrate injection rats were separated and treatment started with carrot juice and insulin nbsp Results and discussion A marked rise in fasting blood glucose as well as serum cholesterol level was observed in diabetic control rats when compared to normal control rats Antihyperglycemic Anti cholesterolmic and haematinic activity observed in carrot juice administered rats on th th st and th days post treatment Anti hyperglycemic and anti cholesterol mic activity was found less effective than that of insulin treatment group nbsp Conclusion It is hope that present investigation will be helpful in establishing a scientific basis for antidiabetic haematinic and Anti cholesterolmic effects in experimental animal model The results are lt statistically significant