抗癌中草药研究进展

S. Tiware, Komal Khond Warghane, Prasad Makde, Harshal Yeskar
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摘要

癌症是人类面临的最重要的健康问题之一,是一种可怕的疾病,需要积极主动的治疗方法。植物是一种新型化学物质的来源,也是癌症研究的一个有前途的课题。尽管化疗取得了成功,但迄今为止仍有一些不利的副作用。然而,利用植物及其产生的产品作为一种简单、安全、成本效益高、节省时间、环保、危害小的传统治疗方法,正在彻底改变这一领域。植物化学物质具有针对肿瘤细胞的选择性活性。这个被称为致癌的复杂过程涉及一系列信号级联反应。植物化学物质以多种方式对靶标事件产生多效性作用,被认为是开发新疗法的有吸引力的前景。“研究人员正在研究这些植物化学物质中的哪些可能抑制或减少癌细胞的生长,而不会造成任何不利的副作用。有很多植物化学物质和它们的类似物已经被确定为潜在的抗癌治疗的可能性。通过这篇简明扼要的综述,我们将重点介绍基于植物分子的靶向核和细胞成分的癌症治疗的最新发展和值得注意的成就。
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Review on anti-cancer herbal drugs
One of the most important health issues facing humanity, cancer is a scary disease that demands a proactive approach to treatment. Plants, a source of novel chemical entities and a promising topic for cancer research. Despite its success, chemotherapy has so far had some unfavourable side effects. However, the use of plants and products generated from them is revolutionising the field as a simple, secure, cost-effective, time-saving, environmentally friendly, and less hazardous alternative to traditional treatment procedures. Phytochemicals have selective activities that are targeted towards tumour cells. The complex process known as carcinogenesis involves a number of signalling cascades. Phytochemicals are thought to be attractive prospects for the development of new therapeutics because of their pleiotropic effects on the target event in a number of ways."Researchers are looking at which of these phytochemicals might be possibilities for inhibiting or reducing the growth of cancer cells without causing any unfavourable side effects. There are a lot of phytochemicals and the analogues they were made from that have been identified as potential anticancer therapeutic possibilities. An effort has been made to highlight the most recent developments and noteworthy accomplishments in phytomolecule-based cancer therapies that target nuclear and cellular components through this succinct overview.
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