抗菌光动力疗法在慢性扁桃体炎治疗中的应用

Е. Еременко, Л. Малец, А. А. Куприянова, И. Журневич, Ю. Плавский, Yuliya E. Yaromenka, Alena L. Malets, Hanna A. Kupryianava, Veronika I. Zhurnevich, Vitaly Y. Plavskii
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引用次数: 1

摘要

一种治疗慢性扁桃体炎的有效方法已被开发出来。该方法是将扁桃体连续暴露于紫色(405 nm波长)和红色(650波长)光谱区域的激光辐射中,功率密度为25 mW/cm,每个扁桃体照射3分钟,持续7天。结果表明,按上述方法进行激光治疗具有良好的抗炎、减充血和抗菌作用。此外,激光辐射的抗菌作用是由于内源性卟啉和黄素光敏剂的激发,主要局限于病原微生物群。这些化合物产生单线态氧的效率高,无需引入外源光敏剂即可实现光的杀菌作用。
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Use of antimicrobial photodynamic therapy in the treatment of chronic tonsillitis
An effective method for treatment of chronic tonsillitis has been developed. It is based on combined (sequential) exposure of the tonsils to laser radiation of violet (405 nm wavelength) and red (650 wavelength) spectral regions at a power density of 25 mW/cm for 3 minutes for each amygdala for 7 days. It was shown that laser therapy according to the above method has positive anti-inflammatory, decongestant and antimicrobial effects. Moreover, the antimicrobial effect of laser radiation is due to the excitation of endogenous porphyrin and flavin photosensitizers, localized mainly in pathogenic microflora. The high efficiency of generation of singlet oxygen by these compounds is capable of realizing the bactericidal action of light without introducing exogenous photosensitizers.
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