A. Murzakhmetova, V. Kemaikin, A. Ainabay, A. Meiramova, B. Ainabekova
{"title":"急性白血病患者造血干细胞移植后急性肾损伤:一系列临床病例","authors":"A. Murzakhmetova, V. Kemaikin, A. Ainabay, A. Meiramova, B. Ainabekova","doi":"10.52532/2663-4864-2022-3-65-32-36","DOIUrl":null,"url":null,"abstract":"Relevance: Acute renal kidney injury is a severe complication in patients with acute leukemia who underwent hematopoietic stem cell \ntransplantation (HSCT). According to statistics, acute renal dysfunction often occurs in the first 100 days after HSCT. \nThis study aimed to evaluate kidney function in patients with acute leukemia after hematopoietic stem cell transplantation. \nMethods: The article presents clinical cases of patients with acute lymphoblastic leukemia who developed acute renal failure after \nHSCT. The dynamics of the functional state of kidneys in patients with acute lymphoblastic leukemia after HSCT are described. \nResults: The acute kidney disorder in the studied patients was mainly caused by HSCT complications. We have identified renal kidney \ndamage in the form of acute tumor lysis and thrombotic microangiopathy. \nConclusion: Patients with acute lymphoblastic leukemia risk developing acute kidney disorder during HSCT, which requires careful \nmonitoring of kidney function, especially in the early post-transplant period","PeriodicalId":19480,"journal":{"name":"Oncologia i radiologia Kazakhstana","volume":"41 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"ACUTE KIDNEY INJURY IN PATIENTS WITH ACUTE LEUKEMIA AFTER HEMATOPOIETIC STEM CELL TRANSPLANTATION: A SERIES OF CLINICAL CASES\",\"authors\":\"A. Murzakhmetova, V. Kemaikin, A. Ainabay, A. Meiramova, B. Ainabekova\",\"doi\":\"10.52532/2663-4864-2022-3-65-32-36\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Relevance: Acute renal kidney injury is a severe complication in patients with acute leukemia who underwent hematopoietic stem cell \\ntransplantation (HSCT). According to statistics, acute renal dysfunction often occurs in the first 100 days after HSCT. \\nThis study aimed to evaluate kidney function in patients with acute leukemia after hematopoietic stem cell transplantation. \\nMethods: The article presents clinical cases of patients with acute lymphoblastic leukemia who developed acute renal failure after \\nHSCT. The dynamics of the functional state of kidneys in patients with acute lymphoblastic leukemia after HSCT are described. \\nResults: The acute kidney disorder in the studied patients was mainly caused by HSCT complications. We have identified renal kidney \\ndamage in the form of acute tumor lysis and thrombotic microangiopathy. \\nConclusion: Patients with acute lymphoblastic leukemia risk developing acute kidney disorder during HSCT, which requires careful \\nmonitoring of kidney function, especially in the early post-transplant period\",\"PeriodicalId\":19480,\"journal\":{\"name\":\"Oncologia i radiologia Kazakhstana\",\"volume\":\"41 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-09-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Oncologia i radiologia Kazakhstana\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.52532/2663-4864-2022-3-65-32-36\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Oncologia i radiologia Kazakhstana","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.52532/2663-4864-2022-3-65-32-36","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
ACUTE KIDNEY INJURY IN PATIENTS WITH ACUTE LEUKEMIA AFTER HEMATOPOIETIC STEM CELL TRANSPLANTATION: A SERIES OF CLINICAL CASES
Relevance: Acute renal kidney injury is a severe complication in patients with acute leukemia who underwent hematopoietic stem cell
transplantation (HSCT). According to statistics, acute renal dysfunction often occurs in the first 100 days after HSCT.
This study aimed to evaluate kidney function in patients with acute leukemia after hematopoietic stem cell transplantation.
Methods: The article presents clinical cases of patients with acute lymphoblastic leukemia who developed acute renal failure after
HSCT. The dynamics of the functional state of kidneys in patients with acute lymphoblastic leukemia after HSCT are described.
Results: The acute kidney disorder in the studied patients was mainly caused by HSCT complications. We have identified renal kidney
damage in the form of acute tumor lysis and thrombotic microangiopathy.
Conclusion: Patients with acute lymphoblastic leukemia risk developing acute kidney disorder during HSCT, which requires careful
monitoring of kidney function, especially in the early post-transplant period
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