{"title":"大剂量甲基强的松龙治疗急性坏死性嗜酸性心肌炎成功。","authors":"Nozomi Watanabe, Susumu Nakagawa, Takashi Fukunaga, Shuji Fukuoka, Kinta Hatakeyama, Tohru Hayashi","doi":"10.1253/JCJ.65.923","DOIUrl":null,"url":null,"abstract":"Acute necrotizing eosinophilic myocarditis is the most severe form of eosinophilic myocarditis, or hypersensitivity myocarditis, and is characterized by rapidly progressive congestive heart failure followed by fulminant clinical deterioration that is nearly always fatal. A 55-year-old previously healthy patient with acute necrotizing eosinophilic myocarditis was diagnosed by early myocardial biopsy and successfully treated with corticosteroids. Throughout his hospitalization, the eosinophil count in the peripheral blood remained normal (56-201/mm3). Early stage corticosteroid therapy can have dramatic effects in acute necrotizing eosinophilic myocarditis and early diagnosis by endomyocardial biopsy is recommended.","PeriodicalId":14544,"journal":{"name":"Japanese circulation journal","volume":"19 1","pages":"923-6"},"PeriodicalIF":0.0000,"publicationDate":"2001-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"42","resultStr":"{\"title\":\"Acute necrotizing eosinophilic myocarditis successfully treated by high dose methylprednisolone.\",\"authors\":\"Nozomi Watanabe, Susumu Nakagawa, Takashi Fukunaga, Shuji Fukuoka, Kinta Hatakeyama, Tohru Hayashi\",\"doi\":\"10.1253/JCJ.65.923\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Acute necrotizing eosinophilic myocarditis is the most severe form of eosinophilic myocarditis, or hypersensitivity myocarditis, and is characterized by rapidly progressive congestive heart failure followed by fulminant clinical deterioration that is nearly always fatal. A 55-year-old previously healthy patient with acute necrotizing eosinophilic myocarditis was diagnosed by early myocardial biopsy and successfully treated with corticosteroids. Throughout his hospitalization, the eosinophil count in the peripheral blood remained normal (56-201/mm3). Early stage corticosteroid therapy can have dramatic effects in acute necrotizing eosinophilic myocarditis and early diagnosis by endomyocardial biopsy is recommended.\",\"PeriodicalId\":14544,\"journal\":{\"name\":\"Japanese circulation journal\",\"volume\":\"19 1\",\"pages\":\"923-6\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2001-09-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"42\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Japanese circulation journal\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1253/JCJ.65.923\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Japanese circulation journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1253/JCJ.65.923","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Acute necrotizing eosinophilic myocarditis successfully treated by high dose methylprednisolone.
Acute necrotizing eosinophilic myocarditis is the most severe form of eosinophilic myocarditis, or hypersensitivity myocarditis, and is characterized by rapidly progressive congestive heart failure followed by fulminant clinical deterioration that is nearly always fatal. A 55-year-old previously healthy patient with acute necrotizing eosinophilic myocarditis was diagnosed by early myocardial biopsy and successfully treated with corticosteroids. Throughout his hospitalization, the eosinophil count in the peripheral blood remained normal (56-201/mm3). Early stage corticosteroid therapy can have dramatic effects in acute necrotizing eosinophilic myocarditis and early diagnosis by endomyocardial biopsy is recommended.
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