纳米疗法在膀胱癌治疗中的应用

Kun Liu, Qixin Mo, Z. Ding, Shicong Lai, Jian Ren, Qingsong Yu
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摘要

膀胱癌(BC)是一种具有多种临床表现和治疗挑战的复杂疾病,目前的标准治疗方法仍然有限且不利。治疗学,即诊断和治疗技术的整合,已成为应对这些挑战的一种有希望的战略。纳米医学的快速发展为减少副作用、增强肿瘤抑制和克服耐药性等改善BC治疗和诊断带来了希望。金属纳米粒子(NPs)、无机纳米粒子、聚合物纳米粒子等各具优势,在BC的治疗中显示出令人鼓舞的潜力。在这篇综述中,我们概述了基于纳米技术的BC治疗的最新进展,为未来BC治疗提供了设计和发现新型NPs的见解。
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Nano theranostics involved in bladder cancer treatment
Bladder cancer (BC) is a complex disease with multiple clinical manifestations and treatment challenges, and current standard-of-care therapies remain limited and unfavorable. Theranostics, the integration of diagnostic and therapeutic technologies, has emerged as a promising strategy to address these challenges. The rapid development of nanomedicine has been a source of hope for the improvement of BC therapies and diagnostics by reducing side effects, enhancing tumor suppression, and overcoming drug resistance. Metal nanoparticles (NPs), inorganic NPs, polymer NPs, etc. have their respective advantages and show encouraging potential in the therapy of BC. In this review, we provide an overview on the state of the art in nanotechnology-based theranostics for BC, offering insights into the design and discovery of novel NPs for future BC management.
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