口服生姜胶囊对女性性功能和性生活质量的影响:一项双盲、随机、安慰剂对照试验

IF 1.2 Q3 Medicine Sexologies Pub Date : 2022-12-01 DOI:10.1016/j.sexol.2022.03.004
Z. Afshar , S. Shahali , H. Rastad
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引用次数: 1

摘要

女性性功能障碍是一个公共卫生问题,它会带来各种生理和心理后果,影响夫妻的生活质量。本研究旨在评价口服生姜胶囊对育龄妇女性功能及性生活质量的影响。方法本随机双盲临床试验于2019年7月至2020年11月在伊朗阿尔博尔兹省卫生保健中心就诊的190名育龄妇女进行。采用女性性功能指数(FSFI)和生活质量问卷(SQOL-F)评估女性基线性功能和性生活质量。参与者被随机分配到干预组,每天四次口服250毫克生姜胶囊,持续四周,对照组在相同的时间内每天服用四次安慰剂(250毫克)胶囊。在干预开始四周后,对女性的性生活质量和性功能进行评估。结果干预组患者在研究开始后4周的性功能平均总分较干预前有明显改善(27.93±4.97 vs30.94±3.43;0.001)。干预组在干预4周后性生活质量较干预前明显改善(93.74±17.84 vs 100.9±11.14,p <0.001),与对照组(100.9 vs 97.2)相比。结论口服生姜胶囊有改善育龄妇女性功能和性生活质量的作用。伊朗临床试验注册中心批准文号:IRCT20191013045086N1(注册日期:2019-12-22)。
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Effects of oral ginger capsule on sexual function and sexual quality of life in women: A double-blinded, randomized, placebo-controlled trial

Background

Women's sexual dysfunction is a public health concern with a variety of physical and psychological consequences that influence couples’ quality of life. The present study is conducted to evaluate the effect of the oral ginger capsule on the sexual function and sexual quality of life of reproductive-age women.

Methods

This randomized, double-blind clinical trial was performed on 190 women of reproductive age refereeing to health care centers of Alborz Province, Iran during July 2019- November 2020. The women's baseline sexual function and sexual quality of life were assessed by the Female Sexual Function Index (FSFI) and sexual quality of life-female (SQOL-F) questionnaire. Participants were randomly assigned to the intervention group which received, 250 mg oral ginger capsules four times a day for four weeks, and the control group was received four placebos (250 mg) capsules every day for the same period of time. Women's sexual quality of life, and sexual function, were evaluated four weeks after the start of the intervention.

Results

The mean total score of sexual function four weeks after the start of the study in the intervention group was significantly improved compared to before the intervention (27.93 ± 4.97 vs30.94 ± 3.43 (p < 0.001). The sexual quality of life in the intervention group was significantly improved after four weeks of intervention, compared to before the intervention (93.74 ± 17.84 vs 100.9 ± 11.14, p < 0.001) and compared to the control group (100.9 vs 97.2).

Conclusions

The findings of this study show that oral ginger capsule has the potential to improve the sexual function and sexual quality of life of reproductive-age women.

Trial registration

Approval number from Iranian Registry of Clinical Trials: IRCT20191013045086N1 (Registration date: 2019-12-22).

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来源期刊
Sexologies
Sexologies PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-
CiteScore
1.80
自引率
16.70%
发文量
48
期刊介绍: Sexologies offers a large panel of information to all health professionals working in the field of sexuality: anatomophysiological and basic research; psychodynamic, cognitive, behavioural and relational evaluations of sexual difficulties; epidemiological, sociological, forensic data; information on new sexoactive molecules; research on sexual physiology, reports on specialized congresses; press and books reviews; ethical aspects; calendar of major events of sexology around the world.
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