新辅助化疗在局部晚期鼻咽癌中的作用

Pratiksha Pawar, Pranay Bhandari, Ameya Bihani, Kunal Gupta, Taha Sethjiwala
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引用次数: 0

摘要

摘要鼻咽癌是一种发生于鼻咽表面及粘膜上皮的罕见肿瘤。鼻咽癌的管理是最大的临床挑战之一,但它是放射敏感和化学敏感的;在放化疗同时进行辅助治疗或不辅助治疗的情况下,可以获得良好的肿瘤控制。本文将重点讨论鼻咽癌新辅助化疗对无病生存期(DFS)、无远处转移生存期和总生存期(OS)的影响,以及新辅助化疗的全身毒性、适应症、方案选择和周期数。
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Role of neo-adjuvant chemotherapy in locally advanced nasopharyngeal carcinoma
Nasopharyngeal carcinoma (NPC) is a rare type of tumor which arises from the surface and lining epithelium of nasopharynx. Management of nasopharyngeal carcinoma is one of the greatest clinical challenges but it is radiosensitive and chemosensitive; excellent tumor control can be attained with radiotherapy with or without adjuvant therapies concurrent chemoradiation therapy. This review will focus on role of neoadjuvant chemotherapy in nasopharyngeal carcinoma on disease free survival (DFS), distant metastases free survival and overall survival (OS) and systemic toxicities, indications and choice and number of cycles of regimen for neoadjuvant chemotherapy.
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来源期刊
CiteScore
0.90
自引率
0.00%
发文量
226
审稿时长
3 months
期刊介绍: Indian Journal of Otolaryngology and Head & Neck Surgery was founded as Indian Journal of Otolaryngology in 1949 as a scientific Journal published by the Association of Otolaryngologists of India and was later rechristened as IJOHNS to incorporate the changes and progress. IJOHNS, undoubtedly one of the oldest Journals in India, is the official publication of the Association of Otolaryngologists of India and is about to publish it is 67th Volume in 2015. The Journal published quarterly accepts articles in general Oto-Rhino-Laryngology and various subspecialities such as Otology, Rhinology, Laryngology and Phonosurgery, Neurotology, Head and Neck Surgery etc. The Journal acts as a window to showcase and project the clinical and research work done by Otolaryngologists community in India and around the world. It is a continued source of useful clinical information with peer review by eminent Otolaryngologists of repute in their respective fields. The Journal accepts articles pertaining to clinical reports, Clinical studies, Research articles in basic and applied Otolaryngology, short Communications, Clinical records reporting unusual presentations or lesions and new surgical techniques. The journal acts as a catalyst and mirrors the Indian Otolaryngologist’s active interests and pursuits. The Journal also invites articles from senior and experienced authors on interesting topics in Otolaryngology and allied sciences from all over the world. The print version is distributed free to about 4000 members of Association of Otolaryngologists of India and the e-Journal shortly going to make its appearance on the Springer Board can be accessed by all the members. Association of Otolaryngologists of India and M/s Springer India group have come together to co-publish IJOHNS from January 2007 and this bondage is going to provide an impetus to the Journal in terms of international presence and global exposure.
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