金属纳米颗粒在糖尿病治疗中的作用

Y. Kumari, Gurmandeep Kaur, Clarisse Ayinkamiye, S. Singh, R. Kumar, R. Khursheed
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引用次数: 0

摘要

糖尿病(DM)是一个众所周知的威胁人类超过2000年。糖尿病是一组以完全缺乏胰岛素、相对缺乏胰岛素或胰岛素抵抗为特征的代谢紊乱。全球糖尿病患病率正以惊人的速度迅速上升,根据国际糖尿病联合会(IDF);预计到2030年,糖尿病将成为全球第七大死因。糖尿病的治疗需要持续监测血糖水平,通过调整饮食糖摄入量和胰岛素治疗来调节血糖水平。目前注射胰岛素的剂量包括每天多达两到三次皮下注射,这可能造成心理压力,导致患者依从性差。目前,一些研究人员一直在关注糖尿病的新管理选择。在这些选择中,金属纳米颗粒的使用因其非侵入性和部位特异性而成为最引人注目和最有前途的选择。金属纳米颗粒具有改善糖尿病患者护理的巨大潜力,因为它允许将胰岛素口服到特定部位,从而提高其生物利用度和药理功效。目前的研究重点是使用金属纳米颗粒口服胰岛素。©2019 igglobal研究与出版基金会。版权所有。本文出处:Kumari, Y.;考尔,g;Ayinkamiye c;辛格”栏目;库马尔,r;金属纳米颗粒在糖尿病治疗中的作用。印度国际制药公司。科学。, 2019;9(2生理):121。DOI: http://doi.org/10.35652/IGJPS.2019.92S19。印度全球药物科学杂志(ISSN 2249 1023;CODENIGJPAI;NLM ID: 101610675)在CrossRef (DOI Enabling), UGC CARE Journal List, EMBASE(Elsevier), National Library of Medicine (NLM) Catalog, ResearchGate, Publons, CAS (ACS), Index哥白尼,Google Scholar等中索引和摘要。欲了解更多详情,请访问http://iglobaljournal.com这是由APTI赞助,印度旁遮普阿姆利则马纳瓦拉斯里赛药学院组织的“RAPSCON-2019”的特刊。以日志形式提供放松。
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Role of Metallic Nanoparticles in the Treatment of Diabetes Mellitus
Diabetes mellitus (DM) is a well-known threat to mankind for more than 2000 years. DM is a group of metabolic disorder characterized by a complete lack of insulin, a relative lack of insulin, or insulin resistance. The prevalence of diabetes is rapidly rising all over the globe at an alarming rate and as per international diabetes federation (IDF); diabetes is expected to become the seventh largest cause of death worldwide by 2030. Treatment of diabetes need constant monitoring of blood glucose level, regulating it through modified dietary sugar intake and insulin therapy. Current dosage of injectable insulin comprises of up to twothree subcutaneous injections per day which can cause psychological stress leading to poor patient compliance. At present several researchers have been focusing on new management options for diabetes. Among these options the use of metallic nanoparticles is becoming an eye catching and most promising due to their non-invasiveness and site specificity. Metallic nanoparticles hold substantial potential for improving the care of patients with diabetes as it allows oral delivery of insulin to the specific site thus increasing its bioavailability and pharmacological efficacies. The current presentation focuses on oral delivery of insulin using metallic nanoparticles. © 2019 iGlobal Research and Publishing Foundation. All rights reserved. Cite this article as: Kumari, Y.; Kaur, G.; Ayinkamiye, C.; Singh, S.K.; Kumar, R.; Khursheed, R. Role of Metallic Nanoparticles in the Treatment of Diabetes Mellitus. Indo Global J. Pharm. Sci., 2019; 9(2Suppl.): 121. DOI: http://doi.org/10.35652/IGJPS.2019.92S19 . Indo Global Journal of Pharmaceutical Sciences( ISSN 2249 1023; CODENIGJPAI; NLM ID: 101610675) indexed and abstracted in CrossRef (DOI Enabling), UGC CARE Journal List, EMBASE(Elsevier), National Library of Medicine (NLM) Catalog, ResearchGate, Publons, CAS (ACS), Index Copernicus, Google Scholar and many more. For further details, visit http://iglobaljournal.com This is a special issue as an outcome of ‘RAPSCON-2019’ sponsored by APTI and organized by Sri Sai College of Pharmacy, Manawala, Amritsar, Punjab, India. Relaxation offered in journal format.
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