索科托Usmanu Danfodiyo大学教学医院新生儿破伤风6年回顾

A. Adamu, M. Ugege, B. Onankpa, T. Yusuf, K. O. Isezuo, F. Jiya, F. Abubakar
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摘要

背景:破伤风是一种疫苗可预防的疾病,但其发病率在发展中国家仍然高得令人无法接受。目的:了解索科托乌斯马努丹弗迪约大学教学医院新生儿破伤风的患病率、危险因素及转归。方法:2010年1月1日至2015年12月31日进行回顾性描述性研究。研究了1个月至15岁诊断为新生儿破伤风的儿童。从录取文件中提取信息。数据分析采用SPSS version 20。结果:研究期间共入院14458人;61人患有新生儿后破伤风,患病率为0.4%。M: F比率为1.5:1。平均年龄7.4±3.2岁。59例(96.7%)未接种破伤风疫苗。其中33例(54.1%)为足部外伤。出院31例(50.8%),DAMA 5例(8.2%),死亡25例(41.0%),病死率41.0%。结论:新生儿后破伤风是索科托地区发病和死亡的主要原因。需要改进卫生教育、免疫方案的可持续性和覆盖面,以根除这一祸害。
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A 6-year review of Post-Neonatal Tetanus at Usmanu Danfodiyo University Teaching Hospital, Sokoto
Background: Tetanus is a vaccine-preventable disease but its incidence has remained unacceptably high in developing countries. Objective: To determine the prevalence, risk factors and outcome of post-neonatal tetanus at Usmanu Danfodiyo University Teaching Hospital (UDUTH), Sokoto. Methods: A retrospective descriptive study from 1st January 2010 to 31st December 2015. Children aged 1 month to 15 years diagnosed with post-neonatal tetanus were studied. Information from the admission files was extracted. Data was analysed using SPSS version 20. Results: Total admissions during the study period were 14,458; 61 had post-neonatal tetanus, giving a prevalence of 0.4%. The M: F ratio was 1.5:1. The mean age was 7.4±3.2 years. Fifty-nine (96.7%) were not immunised against tetanus. Portal of entry for the organism was trauma injuries to the foot in 33(54.1%). Thirty-one (50.8%) were discharged, 5(8.2%) DAMA, while 25(41.0%) died, and case fatality was 41.0%. Conclusion: Post-neonatal tetanus is a major cause of morbidity and mortality in Sokoto. There is need for improved health education, sustainability of immunisation programmes and coverage to eradicate this scourge.
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