Verification of Effectivness of Conservants K 145 and K 702

In our work we dealt with microbial contamination of cosmetics products. Microorganisms have important role in our lives. They are used in food processing and in pharmacy, but their pathogenic triebes can mean health risk for costumers. Hundred thousands of people use cremes every day. That‘s why we think, that this topic is important and results can be relevant for practice. In cosmetics products is sterility not expected, but some of specific microorganisms are controlled. These microorganisms can mean health risk for users. As model microorganism we chose yeast Candida glabrata. Genus Candida can cause oral and genital infections. We could not work with pathogenic triebes so we chose nonpathogenic. We also chose bakteria Escherichia coli, which is an indicator of fecal contamination. If E. coli is in product, it means, that there are lacks of hygiene. Conservants should have same effect against contamination caused by all species of bacterias and yeasts [1,2]. Our aim was verificaion of effectiveness of conservants K 145 and K 702 against contamination caused by mentioned microorganisms. Principle of effect of conservants are chemical reactions with microorganisms. Conservant K 145 has these active substances: 2-Bromo-2-Nitropropane-1.3-Diol, Methylchloroisothiazolinone, Methylisothiazolinone. Conservant K 702 has these active substances: Phenoxyethanol, Benzoic Acid, Dehydroacetic Acid, Ethylhexylglycerin, Polyaminopropyl Biguanide. Every conservant used in the European union has its own maximum authorised concentration. For conservant K 145 this vaule is 0.2%, for conservant K 702 it is 1%. Conservant K 145 is not recommended for products used for mucous membranes and lips and also for toothpastes. Conservant K 702 can be used for leave-on as well as rinse-off products [3,4].