一项基于医院的横断面研究评估血红蛋白、铁谱和甲状腺功能测试在休止期脱发、女性型脱发和斑秃的妇女

B. Amatya, S. Joshi
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引用次数: 1

摘要

简介:脱发是患者看皮肤科医生最常见的抱怨之一。女性脱发的三个最常见原因是休止期脱发、斑秃和女性型脱发。目的:本研究的目的是研究休止期脱发、斑秃和女性型脱发妇女的血红蛋白、铁谱和甲状腺功能测试。材料和方法:这是一项基于医院的横断面研究,在尼泊尔医学院和教学医院(NMCTH)皮肤性病科进行。我们招募了2019年6月至2020年7月期间到我们门诊就诊的患有休止期脱发、斑秃或女性型脱发的女性患者。收集临床和人口统计资料,并调查血红蛋白、血清铁谱和甲状腺功能。结果:在研究期间共招募了80例患者。最常见的诊断是休止期脱发(49例,61.25%),其次是斑秃(18例,22.5%)和女性型脱发(13例,16.25%)。虽然平均血红蛋白水平在正常范围内,但在77.55%的休止期脱发患者、88.89%的斑秃患者和84.61%的女性型脱发患者中发现铁蛋白水平低于正常头发周期。甲状腺异常较少见,超过75%的患者甲状腺功能正常。结论:血红蛋白水平不能代表获得性脱发女性的真实铁状态。因此,我们建议在所有患有休止期脱发、斑秃或女性型脱发的女性中调查铁谱。
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A Hospital Based Cross Sectional Study Evaluating Haemoglobin, Iron Profile and Thyroid Function Tests in Women with Telogen Effluvium, Female Pattern Hair Loss, and Alopecia Areata
Introduction: Hair loss is one of the most frequent complaints for which patients see a dermatologist. The three most common causes of hair loss in women are telogen effluvium, alopecia areata and female pattern hair loss. Objectives: The aim of this study was to investigate haemoglobin, iron profile and thyroid function tests in women with telogen effluvium, alopecia areata and female pattern hair loss. Materials and Methods: This was a hospital based cross sectional study conducted at the Department of Dermatology and Venereology, Nepal Medical College and Teaching Hospital (NMCTH). We recruited female patients with telogen effluvium, alopecia areata or female pattern hair loss who presented to our outpatient department between June 2019 and July 2020. Clinical and demographic data were collected and haemoglobin, serum iron profile and thyroid function investigated. Results: A total of 80 patients were recruited in the study period. The most common diagnosis was telogen effluvium (49, 61.25%) followed by alopecia areata (18, 22.5%) and female pattern hair loss (13, 16.25%). Although mean haemoglobin levels were within normal limits, inadequate ferritin levels for normal hair cycle were found in 77.55% of patients with telogen effluvium, 88.89% with alopecia areata and 84.61% with female pattern hair loss. Thyroid abnormalities were less commonly observed with more than 75% of the patients being euthyroid. Conclusion: Haemoglobin levels are not representative of true iron status in females with acquired alopecia. We therefore recommend investigating iron profile in all females with telogen effluvium, alopecia areata or female pattern hair loss.
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