原甘菊甲醇提取物化学成分分析(茄科)

Thi Thanh Thuy Tran, H. P. Dang, T. Nguyen
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引用次数: 5

摘要

分别用正己烷、乙酸乙酯和甲醇对原甘露进行提取,得到相应的提取物。甲醇溶性提取物加入HCl 0.5M酸化;然后用CHCl3进行液-液分割,得到CHCl3可溶部分。从该馏分中分离得到4个化合物,分别鉴定为过氧化麦角甾醇(1)、9,11-脱氢麦角甾醇(2)、N-(N-苯甲酰- l-苯丙酰)- l-苯丙醇(3)和莫匹尼酰胺(4)。通过核磁共振波谱分析和文献对比对其结构进行了鉴定。所有分离得到的化合物均为首次报道。
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Chemical constituents from methanolic extract of Solanum procumbens Lour (Solanaceae)
Solanum procumbens L. (Solanaceae) were extracted respectively with n-hexane, ethyl acetate, and methanol to obtain the corresponding extracts. The methanol-soluble extract was acidified by adding HCl 0.5M; this was followed by liquid-liquid partition with CHCl3 to afford CHCl3-soluble fraction. From this fraction, four compounds were isolated and identified as ergosterol peroxide (1), 9,11-dehydroergosterol peroxide (2), N-(N-benzoyl-L-phenylalanyl)-L-phenylalanol (3), and moupinamide (4). Their structures were elucidated based on the NMR spectroscopic analysis and comparison with the literature. All isolated compounds were first reported from S. procumbens.
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