Elina Siirola, Fabian Eggimann, Charles Moore, Kirsten Schroer, Alexandra Vargas, Theo Peschke, Thierry Schlama, Radka Snajdrova
{"title":"诺华生物催化技术40年来的发展历程。","authors":"Elina Siirola, Fabian Eggimann, Charles Moore, Kirsten Schroer, Alexandra Vargas, Theo Peschke, Thierry Schlama, Radka Snajdrova","doi":"10.2533/chimia.2023.376","DOIUrl":null,"url":null,"abstract":"<p><p>The fortieth anniversary of biocatalysis started at Ciba-Geigy and later at Novartis is a great time to pause and reflect on development of science and technology in this field. Enzyme-based synthesis became a highly valued enabling tool for pharmaceutical research and development over the last decades. In this perspective we aim to discuss how the scientific approaches and trends evolved over the time and present future challenges and opportunities.</p>","PeriodicalId":76059,"journal":{"name":"Journal of the Royal Naval Medical Service","volume":"49 1","pages":"376-383"},"PeriodicalIF":0.0000,"publicationDate":"2023-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Evolution of Biocatalysis at Novartis over the last 40 Years.\",\"authors\":\"Elina Siirola, Fabian Eggimann, Charles Moore, Kirsten Schroer, Alexandra Vargas, Theo Peschke, Thierry Schlama, Radka Snajdrova\",\"doi\":\"10.2533/chimia.2023.376\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The fortieth anniversary of biocatalysis started at Ciba-Geigy and later at Novartis is a great time to pause and reflect on development of science and technology in this field. Enzyme-based synthesis became a highly valued enabling tool for pharmaceutical research and development over the last decades. In this perspective we aim to discuss how the scientific approaches and trends evolved over the time and present future challenges and opportunities.</p>\",\"PeriodicalId\":76059,\"journal\":{\"name\":\"Journal of the Royal Naval Medical Service\",\"volume\":\"49 1\",\"pages\":\"376-383\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-06-28\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of the Royal Naval Medical Service\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://doi.org/10.2533/chimia.2023.376\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of the Royal Naval Medical Service","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.2533/chimia.2023.376","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Evolution of Biocatalysis at Novartis over the last 40 Years.
The fortieth anniversary of biocatalysis started at Ciba-Geigy and later at Novartis is a great time to pause and reflect on development of science and technology in this field. Enzyme-based synthesis became a highly valued enabling tool for pharmaceutical research and development over the last decades. In this perspective we aim to discuss how the scientific approaches and trends evolved over the time and present future challenges and opportunities.
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